Evidence map›Paper›PMID 33357325›Full record

Trial reportJournal of hospital medicine2021

The Effects of a Multifaceted Intervention to Improve Care Transitions Within an Accountable Care Organization: Results of a Stepped-Wedge Cluster-Randomized Trial.

Jeffrey L Schnipper, Lipika Samal, Nyryan Nolido, Catherine Yoon, Anuj K Dalal, Cherlie Magny-Normilus, Asaf Bitton, Ryan Thompson, Stephanie Labonville, Gwen Crevensten

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of hospital medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Patient- and family-centred care transition interventions for adults: a systematic review and meta-analysis of RCTs.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2023
    Pooled it
  3. Discharge planning from hospital.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Trial
  5. Effect of digital tools to promote hospital quality and safety on adverse events after discharge.Journal of the American Medical Informatics Association : JAMIA · 2024
    Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jeffrey L SchnipperDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Lipika SamalDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Nyryan NolidoDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Catherine YoonDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Anuj K DalalDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Cherlie Magny-NormilusDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Asaf BittonDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, Massachusetts.
Ryan ThompsonHarvard Medical School, Boston, Massachusetts.
Stephanie LabonvillePharmacy Services, Brigham and Women's Hospital, Boston, Massachusetts.
Gwen CrevenstenHarvard Medical School, Boston, Massachusetts.
Brigham and Women's Hospital · USHarvard University · USBoston College · USMassachusetts General Hospital · US

Funding

Self-Management and Glycemic Control in Adult Haitian Immigrants with Type 2 DiabetesK99NR019325 · NINR · BOSTON COLLEGE · PI MAGNY-NORMILUS, CHERLIE · 2020 to 2021
$184k
NINR NIH HHS K99 NR019325
6 · The paper itself

Abstract

backgroundTransitions from hospital to the ambulatory setting are high risk for patients in terms of adverse events, poor clinical outcomes, and readmission.

objectivesTo develop, implement, and refine a multifaceted care transitions intervention and evaluate its effects on postdischarge adverse events. DESIGN, SETTING, AND

participantsTwo-arm, single-blind (blinded outcomes assessor), stepped-wedge, cluster-randomized clinical trial. Participants were 1,679 adult patients who belonged to one of 17 primary care practices and were admitted to a medical or surgical service at either of two participating hospitals within a pioneer accountable care organization (ACO).

interventionsMulticomponent intervention in the 30 days following hospitalization, including inpatient pharmacist-led medication reconciliation, coordination of care between an inpatient "discharge advocate" and a primary care "responsible outpatient clinician," postdischarge phone calls, and postdischarge primary care visit. MAIN OUTCOMES AND MEASURES: The primary outcome was rate of postdischarge adverse events, as assessed by a 30-day postdischarge phone call and medical record review and adjudicated by two blinded physician reviewers. Secondary outcomes included preventable adverse events, new or worsening symptoms after discharge, and 30-day nonelective hospital readmission.

resultsAmong patients included in the study, 692 were assigned to usual care and 987 to the intervention. Patients in the intervention arm had a 45% relative reduction in postdischarge adverse events (18 vs 23 events per 100 patients; adjusted incidence rate ratio, 0.55; 95% CI, 0.35-0.84). Significant reductions were also seen in preventable adverse events and in new or worsening symptoms, but there was no difference in readmission rates.

conclusionA multifaceted intervention was associated with a significant reduction in postdischarge adverse events but no difference in 30-day readmission rates.

Indexed as

AftercarePatient TransferAdultHumansMedication ReconciliationPatient DischargePatient ReadmissionSingle-Blind MethodCare coordinationCare transitionDischarge planningDischarge processInterdisciplinary communicationMedication educationMedication reconciliationReadmission

Identifiers

PMID33357325
PMCPMC7768916
OpenAlexW3116839532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.