ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2021
The use of molecular xenomonitoring for surveillance of mosquito-borne diseases.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Meta-analysis of the prevalence ofFrontiers in cellular and infection microbiology · 2025Pooled it
- The impact of mosquito sampling strategies on molecular xenomonitoring prevalence for filariasis: a systematic review.Bulletin of the World Health Organization · 2024Pooled it
- Xenomonitoring reveals mosquito-host feeding patterns in Serbia.Medical and veterinary entomology · 2026Article
- A recombinase polymerase amplification lateral flow assay (RPA-LF) for detection of Babesia divergens-like parasites.Parasites & vectors · 2026Article
- Assessment of automated loop-mediated isothermal amplification-(LAMP-)based xenomonitoring for Plasmodium spp. in Anopheles mosquitoes.Malaria journal · 2026Article
- Metagenomic profiling unveils the viral diversity in field-collected Aedes larvae from Central India employing nanopore sequencing.Scientific reports · 2026Article
- Molecular xenomonitoring for identifying Plasmodium parasites and blood meal sources of mosquitoes in malaria endemic villages adjacent to the southern Rift Valley Lakes, South Ethiopia.Scientific reports · 2026Article
- Molecular xenosurveillance ofMicrobiology spectrum · 2025Article
- An All-in-One Metabarcoding Approach to Mosquito and Arbovirus Xenosurveillance.Molecular ecology resources · 2025Article
- Vector control at a crossroad: Grappling with multiple challenges.The Indian journal of medical research · 2025Article
- Complementing community science with xenomonitoring: Understanding the eco-epidemiology of Dirofilaria immitis infection in dogs and mosquitoes.Parasites & vectors · 2025Article
- The role of molecular xenomonitoring for assessing the impact of Ivermectin, Diethylcarbamazine Citrate and Albendazole triple-drug treatment against lymphatic filariasis: A cross-sectional study in the Kenyan coastal region.PLOS global public health · 2025Article
- Molecular Xenomonitoring (MX) allows real-time surveillance of West Nile and Usutu virus in mosquito populations.PLoS neglected tropical diseases · 2024Article
- Mosquito bloodmeals can be used to determine vertebrate diversity, host preference, and pathogen exposure in humans and wildlife.Scientific reports · 2024Article
- Isopods infesting Atlantic bonefish (Parasitology · 2024Article
- A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations.Scientific reports · 2024Article
- Postintervention Immunological and Entomological Survey of Lymphatic Filariasis in the City of Olinda, Brazil, 2015-2016.The American journal of tropical medicine and hygiene · 2024Article
- Dengue 1 outbreak in Rosso, northern Senegal, October 2021: entomologic investigations.Journal of medical entomology · 2024Article
- Long-term co-circulation of multiple arboviruses in southeast Australia revealed by xeno-monitoring and viral whole-genome sequencing.Virus evolution · 2024Article
- Development, validation, and pilot application of a high throughput molecular xenomonitoring assay to detectCurrent research in parasitology & vector-borne diseases · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The scientific community recognizes that molecular xenomonitoring (MX) can allow infected mosquitoes to serve as a proxy for human infection in vector-borne disease surveillance, but developing reliable MX systems for programmatic use has been challenging. The primary aim of this article is to examine the available evidence to recommend how MX can best be used for various purposes. Although much of the literature published within the last 20 years focuses on using MX for lymphatic filariasis elimination, a growing body of evidence supports its use in early warning systems for emerging infectious diseases (EIDs). An MX system design must consider the goal and target (e.g. diseases targeted for elimination versus EIDs), mosquito and pathogen characteristics, and context (e.g. setting and health system). MX is currently used as a 'supplement' to human surveillance and will not be considered as a 'replacement' until the correlation between pathogen-infection rates in human and mosquito populations is better understood. Establishing such relationships may not be feasible in elimination scenarios, due to increasingly dwindling human infection prevalence after successful control, but may still be possible for EIDs and in integrated disease surveillance systems. This article is part of the theme issue 'Novel control strategies for mosquito-borne diseases'.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.