Evidence map›Paper›PMID 33356859›Full record

ArticleJournal of dental research2021

Ablation of Pyrophosphate Regulators Promotes Periodontal Regeneration.

A Nagasaki, K Nagasaki, E Y Chu, B D Kear, W D Tadesse, S E Ferebee, L Li, B L Foster, M J Somerman

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

A NagasakiLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID 0000-0002-7655-9658
K NagasakiLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
E Y ChuLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
B D KearLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
W D TadesseLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
S E FerebeeLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
L LiCraniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health (NIH), Bethesda, MD, USA.
B L FosterBiosciences Division, College of Dentistry, The Ohio State University, Columbus, OH, USA.ORCID 0000-0003-3444-0576
M J SomermanLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, USA.
National Institutes of Health · USThe Ohio State University · US

Funding

Functions of extracellular matrix proteins in dental and skeletal mineralizationR01DE027639 · NIDCR · OHIO STATE UNIVERSITY · PI Brian Lee Foster · 2019 to 2026
$2.3M
Role of tissue-nonspecific alkaline phosphatase in dentoalveolar development and diseaseR03DE028411 · NIDCR · OHIO STATE UNIVERSITY · PI FOSTER, BRIAN LEE · 2019 to 2020
$312k
NIDCR NIH HHS K99 DE031148NIDCR NIH HHS R01 DE027639NIDCR NIH HHS R03 DE028411
6 · The paper itself

Abstract

Biomineralization is regulated by inorganic pyrophosphate (PP

Indexed as

DiphosphatesToothTooth AnkylosisAnimalsBone and BonesDental CementumMiceMice, KnockoutDiphosphatesbiomineralizationbone regenerationcementogenesisextracellular matrixosteoclastperiodontium

Identifiers

PMID33356859
PMCPMC8142086
OpenAlexW3118221396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.