Evidence map›Paper›PMID 33356805›Full record

ArticleBioengineered2021

Long non-coding RNA (LncRNA) MRPL23-AS1 promotes tumor progression and carcinogenesis in osteosarcoma by activating Wnt/β-catenin signaling via inhibiting microRNA miR-30b and upregulating myosin heavy chain 9 (MYH9).

Hanwen Zhang, Shuya Liu, Lian Tang, Jianhua Ge, Xiaobo Lu

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  6. Article
  7. Non-Muscle Myosin II A: Friend or Foe in Cancer?International journal of molecular sciences · 2024
    Review
  8. Review
  9. Osteosarcoma in a ceRNET perspective.Journal of biomedical science · 2024
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. MiR-30 Family: A Novel Avenue for Treating Bone and Joint Diseases?International journal of medical sciences · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hanwen ZhangDepartment of Orthopaedics, The Affiliated Hospital of Southwest Medical University , Luzhou City, P.R. China.
Shuya LiuDepartment of Oncology, The Affiliated Hospital of Southwest Medical University , Luzhou City, P.R. China.
Lian TangDepartment of Orthopaedics, The Affiliated Hospital of Southwest Medical University , Luzhou City, P.R. China.
Jianhua GeDepartment of Orthopaedics, The Affiliated Hospital of Southwest Medical University , Luzhou City, P.R. China.
Xiaobo LuDepartment of Orthopaedics, The Affiliated Hospital of Southwest Medical University , Luzhou City, P.R. China.ORCID 0000-0002-1566-7858
Affiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNA (LncRNA) contributes to the occurrence and development of osteosarcoma (OS), although the underlying mechanism is not clear. In the present study, we showed that lncRNA MRPL23-AS1 was remarkably increased in OS tissues and cell lines. Stable knockdown of MRPL23-AS1 evidently attenuated cell viability and invasive ability, meanwhile inhibited

Indexed as

Bone NeoplasmsOsteosarcomaAdultAnimalsbeta CateninBone and BonesCarcinogenesisCell Line, TumorFemaleHumansMaleMiceMicroRNAsMyosin Heavy ChainsRNA, Long NoncodingWnt Signaling Pathwaybeta CateninCTNNB1 protein, humanMicroRNAsMIRN30b microRNA, humanMYH9 protein, humanMyosin Heavy ChainsRNA, Long NoncodingLncRNAMRPL23-AS1osteosarcomaprognosisWnt/β-catenin signaling

Identifiers

PMID33356805
PMCPMC8806232
OpenAlexW3114419192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.