Evidence map›Paper›PMID 33356690›Full record

ReviewCritical reviews in microbiology2021

Ways to control harmful biofilms: prevention, inhibition, and eradication.

Wen Yin, Siyang Xu, Yiting Wang, Yuling Zhang, Shan-Ho Chou, Michael Y Galperin, Jin He

Abstract readReview
In one paragraph

Review in Critical reviews in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Trial
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  4. Review
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  6. Review
  7. Article
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  9. Review
  10. Article
  11. Microorganisms · 2025
    Review
  12. Article
  13. Article
  14. Foods (Basel, Switzerland) · 2025
    Review
  15. Article
  16. Review
  17. Review
  18. Enhancing the destruction ofFrontiers in cellular and infection microbiology · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wen YinState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, PR China.ORCID https://orcid.org/0000-0002-4734-9483
Siyang XuState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, PR China.
Yiting WangState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, PR China.
Yuling ZhangState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, PR China.
Shan-Ho ChouState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, PR China.ORCID https://orcid.org/0000-0002-5202-8238
Michael Y GalperinNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID https://orcid.org/0000-0002-2265-5572
Jin HeState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, PR China.ORCID https://orcid.org/0000-0002-1456-8284

Funding

Comparative Analysis Of Completely Sequenced GenomesZIALM000073 · NLM · NATIONAL LIBRARY OF MEDICINE · PI KOONIN, EUGENE V · 2009 to 2025
$43.1M
COMPARATIVE ANALYSIS OF COMPLETELY SEQUENCED GENOMESZ01LM000073 · NLM · NATIONAL LIBRARY OF MEDICINE · PI KOONIN, EUGENE V · 1996 to 2008
$1.2M
Intramural NIH HHS Z01 LM000073Intramural NIH HHS Z99 LM999999
6 · The paper itself

Abstract

Biofilms are complex microbial architectures that encase microbial cells in a matrix comprising self-produced extracellular polymeric substances. Microorganisms living in biofilms are much more resistant to hostile environments than their planktonic counterparts and exhibit enhanced resistance against the microbicides. From the human perspective, biofilms can be classified into beneficial, neutral, and harmful. Harmful biofilms impact food safety, cause plant and animal diseases, and threaten medical fields, making it urgent to develop effective and robust strategies to control harmful biofilms. In this review, we discuss various strategies to control biofilm formation on infected tissues, implants, and medical devices. We classify the current strategies into three main categories: (i) changing the properties of susceptible surfaces to prevent biofilm formation; (ii) regulating signalling pathways to inhibit biofilm formation; (iii) applying external forces to eradicate the biofilm. We hope this review would motivate the development of innovative and effective strategies for controlling harmful biofilms.

Indexed as

Bacterial Physiological PhenomenaBiofilmsAnimalsAnti-Infective AgentsBacteriaBacterial InfectionsHumansProstheses and ImplantsAnti-Infective Agentsbiofilm controlHarmful biofilminfected tissuemedical devicetissue implant

Identifiers

PMID33356690
PMCPMC7954276

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.