Evidence map›Paper›PMID 33356674›Full record

ReviewExpert opinion on therapeutic targets2021

TAM kinase inhibition and immune checkpoint blockade- a winning combination in cancer treatment?

Pavlos Msaouel, Giannicola Genovese, Jianjun Gao, Suvajit Sen, Nizar M Tannir

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on therapeutic targets, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

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  15. Early death in a mouse model of Alzheimer's disease exacerbated by microglial loss of TAM receptor signaling.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Pavlos MsaouelDepartment of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-6505-8308
Giannicola GenoveseDepartment of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jianjun GaoDepartment of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Suvajit SenExelixis Inc., Alameda, California, USA.
Nizar M TannirDepartment of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
The University of Texas MD Anderson Cancer Center · USExelixis (United States) · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntineoplastic AgentsAxl Receptor Tyrosine KinaseClinical Trials as Topicc-Mer Tyrosine KinaseDrug SynergismHumansImmune Checkpoint InhibitorsMolecular Targeted TherapyNeoplasmsProtein Kinase InhibitorsProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesAntineoplastic AgentsAXL protein, humanAxl Receptor Tyrosine Kinasec-Mer Tyrosine KinaseImmune Checkpoint InhibitorsProtein Kinase InhibitorsProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesTYRO3 protein, humancabozantinibcombination therapyimmune checkpoint inhibitorssitravatinibTAM kinase inhibitors

Identifiers

PMID33356674
PMCPMC12269679
OpenAlexW3117904746

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.