Evidence map›Paper›PMID 33356569›Full record

Trial reportHand (New York, N.Y.)2022

A Multimodal Pain Management Regimen for Open Treatment of Distal Radius Fractures: A Randomized Blinded Study.

Julian Zangrilli, Nura Gouda, Armen Voskerijian, Mark L Wang, Pedro K Beredjiklian, Michael Rivlin

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Hand (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Julian ZangrilliRowan University School of Osteopathic Medicine, Stratford, NJ, USA.ORCID 0000-0003-2140-8024
Nura GoudaRothman Orthopaedic Institute, Philadelphia, PA, USA.
Armen VoskerijianJefferson Surgery Center at The Navy Yard, Philadelphia, PA, USA.
Mark L WangRothman Orthopaedic Institute, Philadelphia, PA, USA.
Pedro K BeredjiklianRothman Orthopaedic Institute, Philadelphia, PA, USA.
Michael RivlinRothman Orthopaedic Institute, Philadelphia, PA, USA.
Rothman Orthopaedics · USBryn Mawr Hospital · USRowan University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdequate pain control is critical after outpatient surgery where patients are not as closely monitored. A multimodal pain management regimen was compared to a conventional pain management method in patients undergoing operative fixation for distal radius fractures. We hypothesized that there would be a decrease in the amount of narcotics used by the multimodal group compared to the conventional pain management group, and that there would be no difference in bone healing postoperatively.

methodsForty-two patients were randomized into 2 groups based on pain protocols. Group 1, the control, received a regional block, acetaminophen, and oxycodone. Group 2 received a multimodal pain regimen consisting of daily doses of pregabalin, celecoxib, and acetaminophen up until postoperative day (POD) #3. They also received a regional block with oxycodone for breakthrough pain.

resultsFrom POD#3 to week 1, there was a significant increase in oxycodone use in the study group correlating with the point in time when the multimodal regimen was discontinued. The shortened Disabilities of the Arm, Shoulder, and Hand Questionnaire (QuickDASH) scores taken at 2 weeks postoperation showed a significantly lower average score in the study group compared to the control. There was no difference in bone healing.

conclusionsThe 2 regimens yielded similar pain control after surgery. The rebound increase in narcotic use after the multimodal regimen was discontinued, and significant difference in QuickDASH scores seen at 2 weeks postoperatively supported that multimodal regimens may not necessarily lead to decreased narcotic use in outpatient upper extremity surgery, but in the short term are shown to improve functional status.

Indexed as

Pain ManagementRadius FracturesAcetaminophenAnalgesics, OpioidCelecoxibHumansNarcoticsOxycodonePostoperative PainPregabalinAcetaminophenAnalgesics, OpioidCelecoxibNarcoticsOxycodonePregabalinbasic sciencediagnosisdisabilitydistal radiusfracture/dislocationpainpain managementresearch and health outcomesspecialtysurgerytraumatreatment

Identifiers

PMID33356569
PMCPMC9608278
OpenAlexW3114671779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.