Evidence map›Paper›PMID 33356117›Full record

ArticleACS infectious diseases2021

Structural and Molecular Dynamics of

Kalistyn H Burley, Bonnie J Cuthbert, Piyali Basu, Jane Newcombe, Ervin M Irimpan, Robert Quechol, Ilona P Foik, David L Mobley, Dany J V Beste, Celia W Goulding

Open access · greenAbstract read
In one paragraph

Article in ACS infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.1field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Significance of Malic Enzyme 1 in Cancer: A Review.Current issues in molecular biology · 2025
    Review
  6. Review
  7. PeerJ · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Kalistyn H BurleyORCID 0000-0002-7885-1812
Bonnie J CuthbertORCID 0000-0001-5176-8245
Piyali BasuDepartment of Microbial and Cellular Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, United Kingdom.
Jane NewcombeDepartment of Microbial and Cellular Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, United Kingdom.
Ervin M Irimpan
Robert Quechol
Dany J V BesteDepartment of Microbial and Cellular Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, United Kingdom.ORCID 0000-0001-6579-1366
University of California, Irvine · USUniversity of Surrey · GB

Funding

Vulnerabilities in Mycobacterial Cell-Wall BiogenesisP01AI095208 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI ZHANG, JUNJIE · 2012 to 2022
$19.8M
Computational alchemy for molecular design and optimizationR01GM108889 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI MOBLEY, DAVID LOWELL · 2014 to 2022
$2.5M
Training Program in Chemical and Structural BiologyT32GM108561 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI POULOS, THOMAS L, TOBIAS, DOUGLAS J · 2014 to 2018
$860k
Medical Research Council MR/K01224X/1NIAID NIH HHS P01 AI095208NIGMS NIH HHS R01 GM108889NIGMS NIH HHS T32 GM108561
6 · The paper itself

Abstract

Tuberculosis (TB) is the most lethal bacterial infectious disease worldwide. It is notoriously difficult to treat, requiring a cocktail of antibiotics administered over many months. The dense, waxy outer membrane of the TB-causing agent,

Indexed as

Mycobacterium tuberculosisPharmaceutical PreparationsTuberculosisAntitubercular AgentsHumansMolecular Dynamics SimulationAntitubercular AgentsPharmaceutical Preparationsanaplerotic nodelipid biosynthesismalic enzymeNAD(P)Hstructure

Identifiers

PMID33356117
PMCPMC8083904
OpenAlexW3117765953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.