Evidence map›Paper›PMID 33355974›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Division and Regrowth of Phase-Separated Giant Unilamellar Vesicles*.

Yannik Dreher, Kevin Jahnke, Elizaveta Bobkova, Joachim P Spatz, Kerstin Göpfrich

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Design of Fuel-Dependent, Complex-Coacervate-Based Synthetic Cells.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  2. Article
  3. Let There be Light! Light as an Engine and Regulator in Synthetic Cells.Angewandte Chemie (International ed. in English) · 2026
    Review
  4. Review
  5. Article
  6. Ion- and Temperature-Programmable Reconfiguration of Subcompartments in Synthetic Cells.Chembiochem : a European journal of chemical biology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Orchestrating Self-Replication in Artificial Cells with Digital Microfluidics.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  11. Review
  12. Flippase-Mediated Hybrid Vesicle Division.Advanced materials (Deerfield Beach, Fla.) · 2025
    Article
  13. Review
  14. Thermally Driven Dynamic Behaviors in Polymeric Vesicles.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Polysaccharide functionalization reduces lipid vesicle stiffness.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  19. Article
  20. Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yannik DreherBiophysical Engineering Group, Max Planck Institute for Medical Research, Jahnstraße 29, 69120, Heidelberg, Germany.ORCID 0000-0002-5614-5036
Kevin JahnkeBiophysical Engineering Group, Max Planck Institute for Medical Research, Jahnstraße 29, 69120, Heidelberg, Germany.ORCID 0000-0001-7311-6993
Elizaveta BobkovaBiophysical Engineering Group, Max Planck Institute for Medical Research, Jahnstraße 29, 69120, Heidelberg, Germany.ORCID 0000-0002-8779-6069
Joachim P SpatzDepartment of Cellular Biophysics, Max Planck Institute for Medical Research, Jahnstraße 29, 69120, Heidelberg, Germany.ORCID 0000-0003-3419-9807
Kerstin GöpfrichBiophysical Engineering Group, Max Planck Institute for Medical Research, Jahnstraße 29, 69120, Heidelberg, Germany.ORCID 0000-0003-2115-3551

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Success in the bottom-up assembly of synthetic cells will depend on strategies for the division of protocellular compartments. Here, we describe the controlled division of phase-separated giant unilamellar lipid vesicles (GUVs). We derive an analytical model based on the vesicle geometry, which makes four quantitative predictions that we verify experimentally. We find that the osmolarity ratio required for division is

Indexed as

DNA structuresGUV divisionosmosissynthetic biologyvesicles

Identifiers

PMID33355974
PMCPMC8252472

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.