Evidence map›Paper›PMID 33355852›Full record

ArticleAsian spine journal2021

Neuromuscular Scoliosis: Comorbidities and Complications.

Karen Andrea Weissmann, Virginie Lafage, Carlos Barrios Pitaque, Renaud Lafage, Carlos M Huaiquilaf, Bryan Ang, Ronald G Schulz

Open access · diamondAbstract read
In one paragraph

Article in Asian spine journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
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  7. The indication of fusion to the pelvis in neuromuscular scoliosis is based on the underlying disease rather than on pelvic obliquity.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
    Article
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  11. Pulmonary Involvement in Neuromuscular Diseases: A Review.Iranian journal of child neurology · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Karen Andrea WeissmannEscuela de Doctorado, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain.
Virginie LafageDepartment of Surgery, Hospital for Special Surgery, New York, NY, USA.
Carlos Barrios PitaqueEscuela de Doctorado, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain.
Renaud LafageDepartment of Surgery, Hospital for Special Surgery, New York, NY, USA.
Carlos M HuaiquilafHospital Exequiel Gonzalez Cortés, Redsalud, Santiago, Chile.
Bryan AngDepartment of Surgery, Hospital for Special Surgery, New York, NY, USA.
Ronald G SchulzDepartamento de Ortopedia y Traumatología, Universidad de Chile, Santiago, Chile.
Hospital for Special Surgery · USValencia Catholic University Saint Vincent Martyr · ESUniversity of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSingle-center, retrospective cohort study conducted from 2013 to 2017. PURPOSE: To determine the risk factors for surgical complications in neuromuscular scoliosis based on known patient comorbidities. OVERVIEW OF LITERATURE: The concept of neuromuscular scoliosis includes a wide variety of pathologies affecting the neuromuscular system. Complications are numerous and are often difficult to predict.

methodsA retrospective analysis of a single-center database was conducted from 2013 to 2017. Inclusion criteria were patients aged <25 years, diagnosis of neuromuscular scoliosis, and history of posterior fusion deformity surgery. A total of 64 patients (mean age, 15 years; 63% females) were included in this study. Clinical, radiological, and laboratory parameters in the preoperative, intraoperative, and postoperative settings were analyzed. Univariate analysis was performed using Student t-test for continuous variables, and a chi-square test was used for noncontinuous variables. Multivariate analysis was performed to identify predictors of major, mechanical, and total complications.

resultsComplications were found in 44% of patients, with 46.9% consisting of major complications, and 84.4% being early complications. Univariate analysis revealed that the presence of perinatal comorbidities, independent of other comorbidities, increased the risk for complications (p=0.029). Preoperative hypoglycemia, high number of instrumented levels, longer surgical time, use of an all-screw construct, lower preoperative pelvic obliquity, postoperative lower kyphosis, high thoracic spinopelvic angle (as measured by T9 spino-pelvic inclination), absence of deep drain, and use of superficial drain were associated with postoperative complications (all p<0.05). Logistic regression demonstrated that comorbidities, longer surgical time, hypoglycemia, and absence of deep drains are predictors of complications. Independent variables that predicted major complications were the number of levels fused, postoperative kyphosis (p=0.025; odds ratio [OR], 1.074), and high screw density (p=0.014; OR, 4.380).

conclusionsComplications in neuromuscular scoliosis are increased by comorbidities, long surgical time, and inadequate correction. Preventative measures to decrease these complications include appropriate preoperative patient preparation and surgical planning.

Indexed as

ComorbidityComplicationsPerinatalScoliosis

Identifiers

PMID33355852
PMCPMC8696062
OpenAlexW3115135880

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.