Evidence map›Paper›PMID 33355851›Full record

ArticleAsian spine journal2021

Study of Patients with Bilateral Knee Osteoarthritis Undergoing Total Knee Replacement Procedure with Coexisting Lumbar Spondylosis Symptoms.

Sanjay Bhalchandra Londhe, Ravi Vinod Shah, Meghana Patwardhan, Amit Pankaj Doshi, Shubhankar Sanjay Londhe, Kavita Subhedar, Vishal Kundnani, Jwalant Patel

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Asian spine journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05464134 (Incidence of Lumbar Spondylolisthesis in Patients Candidate for Total Knee Replacement), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05464134 unknown statusnot on this mapstarted 2023, after this paper: background citation

Incidence of Lumbar Spondylolisthesis in Patients Candidate for Total Knee Replacement

TypeobservationalSponsorAssiut UniversityRan2023 to 2024Enrolled60ConditionsLumbar SpondylolisthesisArmsx-ray
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Back in the game: analyzing performance outcomes following spinal surgery in WNBA athletes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sanjay Bhalchandra LondheDepartment of Orthopedic Surgery, Holy Spirit Hospital, Mumbai, India.
Ravi Vinod ShahDepartment of Orthopedic Surgery, Criticare Hospital, Mumbai, India.
Meghana PatwardhanDepartment of Pain Medicine and Anesthesia, Criticare Hospital, Mumbai, India.
Amit Pankaj DoshiDepartment of Product Management, Meril Lifesciences, Mumbai, India.
Shubhankar Sanjay LondheDepartment of Computer Science, The Vishwanath Karad MIT World Peace University, Pune, India.
Kavita SubhedarDepartment of Clinical Data Management, Criticare Hospital, Mumbai, India.
Vishal KundnaniDivision of Spine Surgery, Department of Orthopaedics, Bombay Hospital, Mumbai, India.
Jwalant PatelDivision of Spine Surgery, Department of Orthopaedics, Bombay Hospital, Mumbai, India.
Bombay Hospital · INHoly Spirit Hospital · INMeril Life Sciences (India) · INMIT World Peace University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designThis is a prospective cohort study involving patients who were followed for 2 years after total knee replacement (TKR) to determine changes in lumbar spine and knee symptoms. PURPOSE: The objectives of this study were to determine the percentage of patients undergoing bilateral TKR who present with coexisting lumbar spine problems and determine if TKR relieves lumbar spine symptoms. OVERVIEW OF LITERATURE: No studies quantify the percentage of TKR patients who experience relief of lumbar spine symptoms after TKR surgery.

methodsThe study included 200 patients (164 females, 36 males) undergoing primary TKR. Follow-up was performed at 4 weeks, 3, 6, 12, and 24 months. Lumbar spine and knee symptom improvements were assessed using the Oswestry Disability Index (ODI) and Oxford Knee Score, respectively.

resultsAll 200 patients undergoing bilateral TKR presented with radiographic lumbar spine degenerative pathology; 60% (n=120) of the patients presented with moderate to severe clinical symptoms of lumbar spondylosis, including 54% (n=108) with degenerative lumbar spondylosis and lumbar canal stenosis and 6% (n=12) with degenerative spondylolisthesis. Of the 120 patients who presented with lumbar spine problems, 90% (n=108) reported improvement in their symptoms; the ODI score improved from 42.5%±4.1% preoperative score to 15.6%±2.3% postoperative score (p-value<0.001). Of the 12 patients with no improvement, 10 patients underwent percutaneous procedures for their lumbar spine pathology with good results, one patient underwent surgery, and one declined any intervention.

conclusionsA significant number of patients (60%) undergoing bilateral TKR also present with symptomatic lumbar spine problems. Patients with mild to moderate lumbar spine degenerative symptoms and no associated severe radiating pain on activity are more likely to experience relief of their symptoms post-TKR.

Indexed as

Lumbar disc degenerationOsteoarthritisTotal knee replacement

Identifiers

PMID33355851
PMCPMC8696049
OpenAlexW3115111485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.