Evidence map›Paper›PMID 33355811›Full record

SynthesisBrazilian journal of cardiovascular surgery2021

Extracorporeal Membrane Oxygenation in COVID-19 Treatment: a Systematic Literature Review.

Tatiana Farias de Oliveira, Carlos Alberto de Oliveira Rocha, Aisla Graciele Galdino Dos Santos, Luiz Carlos Francelino Silva, Saulo Henrique Salgueiro de Aquino, Euclides José Oliveira da Cunha, Rafaela Campos Alcântara, Rodrigo da Rosa Mesquita, Gabriel Monteiro Arnozo, Fernanda Mayara Santos Santana and 2 more

Open access · diamondAbstract readSystematic Review
In one paragraph

Synthesis in Brazilian journal of cardiovascular surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Tatiana Farias de OliveiraDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Carlos Alberto de Oliveira RochaDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Aisla Graciele Galdino Dos SantosDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Luiz Carlos Francelino SilvaDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Saulo Henrique Salgueiro de AquinoDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Euclides José Oliveira da CunhaDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Rafaela Campos AlcântaraDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Rodrigo da Rosa MesquitaDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Gabriel Monteiro ArnozoDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Fernanda Mayara Santos SantanaDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Etvaldo Rodrigues da SilvaDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Carlos Dornels Freire de SouzaDepartment of Medicine, Universidade Federal de Alagoas, Arapiraca, Alagoas, Brazil.
Universidade Federal de Alagoas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe present study intends to systematically review the literature on the use of extracorporeal membrane oxygenation (ECMO) in patients with coronavirus disease 2019 (COVID-19).

methodsThe research was carried out according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA). Studies were selected from PubMed/MEDLINE and LILACS databases between December 2019 and May 17 2020, using the descriptors "ECMO AND COVID-19", "Extracorporeal Membrane Oxygenation AND COVID-19", "ECLS AND COVID-19", and "Extracorporeal Life Support AND COVID-19". Exclusion criteria were government epidemiological bulletins, comments, literature reviews, and articles without full access to content.

resultsTwo hundred and thirty-three scientific productions were found, however only 18 did not met the exclusion criteria and could be included in this study, amouting to a total of 911 patients - 624 (68.5%) men, 261 (28.6%) women, and 26 (2.8%) without sex information. The mean age of the patients was 53.7 years. ECMO was necessary in 274 (30.1%) people (200 [73%] submitted to veno-venous ECMO, nine [3.3%] to veno-arterial ECMO, and seven [2.5%] moved between these two types or needed a more specific ECMO according to the disease prognosis). Five studies did not specify the type of ECMO used, amounting 57 (20.8%) patients. Five patients (1.8%) were discharged, 77 (28.1%) died, 125 (45.6%) remained hospitalized until publication time of their respective studies, and 67 patients (24.4%) had no outcome information.

conclusionIt is evident that more research, covering larger populations, must be carried out in order to clearly elucidate the role of ECMO in the treatment of COVID-19.

Indexed as

COVID-19Extracorporeal Membrane OxygenationFemaleHumansMaleMiddle AgedPrognosisSARS-CoV-2Coronavirus InfectionsCOVID-19Extracorporeal Membrane OxygenationPatient Discharge

Identifiers

PMID33355811
PMCPMC8357376
OpenAlexW3117412766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.