Evidence map›Paper›PMID 33355713›Full record

Trial reportEuropean journal of applied physiology2021

Effect of normobaric hypoxic exercise on blood pressure in old individuals.

Markus Hein, Kristine Chobanyan-Jürgens, Uwe Tegtbur, Stefan Engeli, Jens Jordan, Sven Haufe

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of applied physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02196623 (Hypoxia and Aerobic Exercise Interactions in Age-related Metabolic Muscle Dysfunction), which is not on this map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02196623 nacompletednot on this map

Hypoxia and Aerobic Exercise Interactions in Age-related Metabolic Muscle Dysfunction

TypeinterventionalSponsorHannover Medical SchoolRan2015 to 2019Enrolled29ConditionsElderly PersonsArmsHypoxic exercise, Normoxic Exercise
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  5. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Markus HeinInstitute of Sports Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Kristine Chobanyan-JürgensInstitute of Clinical Pharmacology, Hannover Medical School, Hannover, Germany.
Uwe TegtburInstitute of Sports Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Stefan EngeliInstitute of Clinical Pharmacology, Hannover Medical School, Hannover, Germany.
Jens JordanInstitute of Aerospace Medicine, German Aerospace Center and University of Cologne, Cologne, Germany.
Sven HaufeInstitute of Sports Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Haufe.sven@mh-hannover.de.ORCID http://orcid.org/0000-0002-5259-4352
Medizinische Hochschule Hannover · DEHeidelberg University · DEUniversity of Cologne · DE

Funding

Deutsche Forschungsgemeinschaft HA 7037/ 2-1
6 · The paper itself

Abstract

purposeTo test the hypothesis that the combination of endurance training and hypoxia leads to greater improvements in resting and exercise blood pressure in old sedentary individuals compared to endurance training only.

methodsWe randomly assigned 29 old overweight participants (age: 62 ± 6 years, body mass index (BMI): 28.5 ± 0.5 kg/m

resultsWork rate, heart rate and perceived exertion during training were similar in both groups, with lower oxygen saturation for participants exercising under hypoxia (88.7 ± 1.5 vs. 96.2 ± 1.2%, t(27) = - 13.04, p < 0.001, |g|= 4.85). Office blood pressure and blood pressure during incremental exercise tests did not change significantly in either group after the training program. Systolic blood pressure during the constant work rate test was reduced after training in hypoxia (160 ± 18 vs. 151 ± 14 mmHg, t(13) = 2.44 p < 0.05, |d|= 0.55) but not normoxia (154 ± 22 vs. 150 ± 16 mmHg, t(14) = 0.75, p = 0.46, |d|= 0.18) with no difference between groups over time (F = 0.08, p = 0.77, η

conclusionIn old individuals hypoxia in addition to exercise does not have superior effects on office or exercise blood pressure compared to training in normoxia. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov No. NCT02196623 (registered 22 July 2014).

Indexed as

AgedBlood PressureExerciseFemaleHeart RateHumansMaleMiddle AgedOxygenOxygen ConsumptionSingle-Blind MethodOxygenBlood pressureElderlyExerciseHypoxia

Identifiers

PMID33355713
PMCPMC7892684
OpenAlexW3117500396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.