ArticleBrain structure & function2021
Morphological and functional variability in central and subcentral motor cortex of the human brain.
Article in Brain structure & function, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- White matter variability, cognition, and disorders: a systematic review.Brain structure & function · 2022Pooled it
- High-resolution cortical mapping within and across the central sulcus using 1024-electrode micro-electrocorticography arrays: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Characterization of the Central Sulcus Pli-De-Passage Fronto-Pariétal Moyen in > 1000 Human Brains.Human brain mapping · 2026Article
- How do infant brains fold? Sulcal deepening is linked to development of sulcal span, thickness, curvature, and microstructure.Communications biology · 2026Article
- The inferior frontal sulcus in the chimpanzee brain: morphological examination and association with oro-facial communication.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Structures of the nerve fiber bundles near the central sulcus on diffusion tensor imaging.IBRO neuroscience reports · 2025Article
- Neural Plasticity Induced by Working Memory Training: Insights From Cortical Microstructure and Transcriptional Profiles.CNS neuroscience & therapeutics · 2025Article
- Article
- Anchoring Functional Connectivity to Individual Sulcal Morphology Yields Insights in a Pediatric Study of Reasoning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Eye Movements in Silent Visual Speech Track Unheard Acoustic Signals and Relate to Hearing Experience.eNeuro · 2025Article
- Anchoring functional connectivity to individual sulcal morphology yields insights in a pediatric study of reasoning.bioRxiv : the preprint server for biology · 2025Article
- Neuroplasticity in Diffuse Low-grade Gliomas: Backward Modelling of Brain-tumor Interactions Prior to Diagnosis is Needed to Better Predict Recovery after Treatment.Current neurology and neuroscience reports · 2025Review
- Emotion-related impulsivity is related to orbitofrontal cortical sulcation.Cortex; a journal devoted to the study of the nervous system and behavior · 2024Article
- Morphological patterns and spatial probability maps of the inferior frontal sulcus in the human brain.Human brain mapping · 2024Article
- Phylogenetic differences in the morphology and shape of the central sulcus in great apes and humans: implications for the evolution of motor functions.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- What do brain endocasts tell us? A comparative analysis of the accuracy of sulcal identification by experts and perspectives in palaeoanthropology.Journal of anatomy · 2024Article
- Individual differences, missing sulci, and nomenclature: A comment on "On presentation of the human cerebral sulci from inside the cerebrum".Journal of anatomy · 2023Article
- Article
- Beyond Broca: neural architecture and evolution of a dual motor speech coordination system.Brain : a journal of neurology · 2023Article
- Sulcal depth in prefrontal cortex: a novel predictor of working memory performance.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
Abstract
There is a long-established link between anatomy and function in the somatomotor system in the mammalian cerebral cortex. The morphology of the central sulcus is predictive of the location of functional activation peaks relating to movement of different effectors in individuals. By contrast, morphological variation in the subcentral region and its relationship to function is, as yet, unknown. Investigating the subcentral region is particularly important in the context of speech, since control of the larynx during human speech production is related to activity in this region. Here, we examined the relationship between morphology in the central and subcentral region and the location of functional activity during movement of the hand, lips, tongue, and larynx at the individual participant level. We provide a systematic description of the sulcal patterns of the subcentral and adjacent opercular cortex, including the inter-individual variability in sulcal morphology. We show that, in the majority of participants, the anterior subcentral sulcus is not continuous, but consists of two distinct segments. A robust relationship between morphology of the central and subcentral sulcal segments and movement of different effectors is demonstrated. Inter-individual variability of underlying anatomy might thus explain previous inconsistent findings, in particular regarding the ventral larynx area in subcentral cortex. A surface registration based on sulcal labels indicated that such anatomical information can improve the alignment of functional data for group studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.