Evidence map›Paper›PMID 33355689›Full record

Trial reportEuropean journal of nutrition2021

Can the supplementary consumption of baobab (Adansonia digitata L.) fruit pulp improve the hemoglobin levels and iron status of schoolchildren in Kenya? Findings of a randomized controlled intervention trial.

Esther Charlotte Evang, Tsige-Yohannes Habte, Willis Omondi Owino, Michael Bernhardt Krawinkel

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
7.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Nutrients · 2022
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Esther Charlotte EvangInstitute of Nutritional Sciences, Justus Liebig University Giessen, Wilhelmstr. 20, 35392, Giessen, Germany.ORCID http://orcid.org/0000-0001-5323-9902
Tsige-Yohannes HabteInstitute of Nutritional Sciences, Justus Liebig University Giessen, Wilhelmstr. 20, 35392, Giessen, Germany.
Willis Omondi OwinoSchool of Food and Nutritional Sciences, Jomo Kenyatta University of Agriculture and Technology, Juja, 62000-00200, Nairobi, Kenya.ORCID http://orcid.org/0000-0002-7032-5674
Michael Bernhardt KrawinkelInstitute of Nutritional Sciences, Justus Liebig University Giessen, Wilhelmstr. 20, 35392, Giessen, Germany. michael.krawinkel@uni-giessen.de.ORCID http://orcid.org/0000-0001-5801-4876
Justus-Liebig-Universität Gießen · DEJomo Kenyatta University of Agriculture and Technology · KE

Funding

Bundesministerium für Ernährung und Landwirtschaft FKZ 2813FSNU08Wellcome Trust
6 · The paper itself

Abstract

purposeIn the rural Kenyan diet, the bioavailability of iron is low and predisposes the population to iron deficiency. Fruit pulp of the indigenous baobab tree contains significant amounts of vitamin C, which enhances non-heme iron bioavailability. We studied the impact of baobab fruit pulp (BFP) consumption on the hemoglobin (Hb) and iron status of Kenyan schoolchildren.

methodsThe single-blind randomized controlled intervention trial was implemented daily among apparently healthy schoolchildren aged 6-12 years with hemoglobin level < 12.2 g/dl. For 12 weeks, children in the intervention group (n = 29) received a drink with BFP, while the control group (n = 29) received an isoenergy drink without BFP. At baseline and endline, blood samples were taken.

resultsThe development of hemoglobin, ferritin (FER) and soluble transferrin receptor (sTfR) did not differ significantly between the intervention and control groups. However, in the intervention group, Hb levels improved slightly (2.2%), while they decreased slightly (1.2%) in the control group. Levels of geometric means of sTfR remained almost unchanged (0.7%) in the intervention group and slightly worsened (2.7%) in the control group. In both the groups, geometric mean of FER levels decreased, yet to a smaller extent in the intervention (17.3%) than in the control (26.0%) group.

conclusionEven though no significant effects of BFP could be detected in this study, the identification of products such as BFP remains pertinent to help improve non-heme iron absorption in the most vulnerable populations.

Indexed as

AdansoniaAnemia, Iron-DeficiencyChildFruitHemoglobinsHumansIronKenyaSingle-Blind MethodHemoglobinsIronAnemiaBaobabBioavailabilityKenyaSchoolchildren

Identifiers

PMID33355689
PMCPMC8275536
OpenAlexW3117244584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.