ArticlePlant & cell physiology2021
Autophagy Contributes to the Quality Control of Leaf Mitochondria.
Article in Plant & cell physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Chloroplast stress caused by maltose hyperaccumulation activates chlorophagy via the core autophagy machinery.Plant physiology · 2026Article
- Selective degradation processes in plants are not limited to autophagy.Plant cell reports · 2026Review
- TheProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Microautophagy: current understanding of its molecular mechanisms and functions.Autophagy reports · 2026Review
- Live-Cell Monitoring of Piecemeal Chloroplast Autophagy.Bio-protocol · 2025Article
- Plant-specific mitochondrial fission machinery connects mitochondrial dynamics and mitophagosome formation for piecemeal mitophagy.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Can autophagy enhance crop resilience to environmental stress?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Cytoplasmic inheritance: The transmission of plastid and mitochondrial genomes across cells and generations.Plant physiology · 2025Review
- Mitophagy in plants: Emerging regulators of mitochondrial targeting for selective autophagy.Journal of microscopy · 2025Review
- Proteomics revealed novel functions and drought tolerance of Arabidopsis thaliana protein kinase ATG1.BMC biology · 2025Article
- Article
- Vacuolar degradation of plant organelles.The Plant cell · 2024Review
- Evolution and maintenance of mtDNA gene content across eukaryotes.The Biochemical journal · 2024Review
- Autophagy in plants.Autophagy reports · 2024Review
- Transcriptional and post-translational regulation of plant autophagy.Journal of experimental botany · 2023Review
- Autophagy during maize endosperm development dampens oxidative stress and promotes mitochondrial clearance.Plant physiology · 2023Article
- AlfalfaInternational journal of molecular sciences · 2023Article
- Selective autophagy regulates chloroplast protein import and promotes plant stress tolerance.The EMBO journal · 2023Article
- Autophagic degradation of membrane-bound organelles in plants.Bioscience reports · 2023Review
- Improving two-photon excitation microscopy for sharper and faster biological imaging.Biophysics and physicobiology · 2023Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In autophagy, cytoplasmic components of eukaryotic cells are transported to lysosomes or the vacuole for degradation. Autophagy is involved in plant tolerance to the photooxidative stress caused by ultraviolet B (UVB) radiation, but its roles in plant adaptation to UVB damage have not been fully elucidated. Here, we characterized organellar behavior in UVB-damaged Arabidopsis (Arabidopsis thaliana) leaves and observed the occurrence of autophagic elimination of dysfunctional mitochondria, a process termed mitophagy. Notably, Arabidopsis plants blocked in autophagy displayed increased leaf chlorosis after a 1-h UVB exposure compared to wild-type plants. We visualized autophagosomes by labeling with a fluorescent protein-tagged autophagosome marker, AUTOPHAGY8 (ATG8), and found that a 1-h UVB treatment led to increased formation of autophagosomes and the active transport of mitochondria into the central vacuole. In atg mutant plants, the mitochondrial population increased in UVB-damaged leaves due to the cytoplasmic accumulation of fragmented, depolarized mitochondria. Furthermore, we observed that autophagy was involved in the removal of depolarized mitochondria when mitochondrial function was disrupted by mutation of the FRIENDLY gene, which is required for proper mitochondrial distribution. Therefore, autophagy of mitochondria functions in response to mitochondrion-specific dysfunction as well as UVB damage. Together, these results indicate that autophagy is centrally involved in mitochondrial quality control in Arabidopsis leaves.
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