Evidence map›Paper›PMID 33355274›Full record

ArticleCMAJ open

COVID-19 screening of asymptomatic patients admitted through emergency departments in Alberta: a prospective quality-improvement study.

Pietro Ravani, Lynora Saxinger, Uma Chandran, Kevin Fonseca, Stephanie Murphy, Eddy Lang, Laura McDougall, Braden Manns

Open access · diamondAbstract readMulticenter Study
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. SARS-CoV-2 in children and their accompanying caregivers: Implications for testing strategies in resource limited hospitals.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2022
    Article
  4. Observational
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Pietro RavaniDepartments of Medicine (Ravani, Manns) and Community Health Sciences (Ravani, Manns), and O'Brien Institute for Public Health (Ravani, Manns), and Libin Cardiovascular Institute of Alberta (Ravani, Manns), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine, and Medical Microbiology and Immunology (Saxinger, Chandran), Faculty of Medicine and Dentistry, University of Alberta; Infection Prevention and Control (Chandran), Alberta Health Services, Edmonton, Alta.; Department of Microbiology, Immunology and Infectious Diseases (Fonseca), Cumming School of Medicine, University of Calgary; Alberta Precision Laboratories Calgary (Fonseca), Alberta Health Services, Calgary, Alta.; National Microbiology Laboratory (Murphy), Public Health Agency of Canada; Alberta Precision Laboratories Edmonton (Murphy), Alberta Health Services, Edmonton, Alta.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Alberta Health Services (McDougall), Edmonton, Alta. pravani@ucalgary.ca.
Lynora SaxingerDepartments of Medicine (Ravani, Manns) and Community Health Sciences (Ravani, Manns), and O'Brien Institute for Public Health (Ravani, Manns), and Libin Cardiovascular Institute of Alberta (Ravani, Manns), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine, and Medical Microbiology and Immunology (Saxinger, Chandran), Faculty of Medicine and Dentistry, University of Alberta; Infection Prevention and Control (Chandran), Alberta Health Services, Edmonton, Alta.; Department of Microbiology, Immunology and Infectious Diseases (Fonseca), Cumming School of Medicine, University of Calgary; Alberta Precision Laboratories Calgary (Fonseca), Alberta Health Services, Calgary, Alta.; National Microbiology Laboratory (Murphy), Public Health Agency of Canada; Alberta Precision Laboratories Edmonton (Murphy), Alberta Health Services, Edmonton, Alta.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Alberta Health Services (McDougall), Edmonton, Alta.
Uma ChandranDepartments of Medicine (Ravani, Manns) and Community Health Sciences (Ravani, Manns), and O'Brien Institute for Public Health (Ravani, Manns), and Libin Cardiovascular Institute of Alberta (Ravani, Manns), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine, and Medical Microbiology and Immunology (Saxinger, Chandran), Faculty of Medicine and Dentistry, University of Alberta; Infection Prevention and Control (Chandran), Alberta Health Services, Edmonton, Alta.; Department of Microbiology, Immunology and Infectious Diseases (Fonseca), Cumming School of Medicine, University of Calgary; Alberta Precision Laboratories Calgary (Fonseca), Alberta Health Services, Calgary, Alta.; National Microbiology Laboratory (Murphy), Public Health Agency of Canada; Alberta Precision Laboratories Edmonton (Murphy), Alberta Health Services, Edmonton, Alta.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Alberta Health Services (McDougall), Edmonton, Alta.
Kevin FonsecaDepartments of Medicine (Ravani, Manns) and Community Health Sciences (Ravani, Manns), and O'Brien Institute for Public Health (Ravani, Manns), and Libin Cardiovascular Institute of Alberta (Ravani, Manns), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine, and Medical Microbiology and Immunology (Saxinger, Chandran), Faculty of Medicine and Dentistry, University of Alberta; Infection Prevention and Control (Chandran), Alberta Health Services, Edmonton, Alta.; Department of Microbiology, Immunology and Infectious Diseases (Fonseca), Cumming School of Medicine, University of Calgary; Alberta Precision Laboratories Calgary (Fonseca), Alberta Health Services, Calgary, Alta.; National Microbiology Laboratory (Murphy), Public Health Agency of Canada; Alberta Precision Laboratories Edmonton (Murphy), Alberta Health Services, Edmonton, Alta.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Alberta Health Services (McDougall), Edmonton, Alta.
Stephanie MurphyDepartments of Medicine (Ravani, Manns) and Community Health Sciences (Ravani, Manns), and O'Brien Institute for Public Health (Ravani, Manns), and Libin Cardiovascular Institute of Alberta (Ravani, Manns), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine, and Medical Microbiology and Immunology (Saxinger, Chandran), Faculty of Medicine and Dentistry, University of Alberta; Infection Prevention and Control (Chandran), Alberta Health Services, Edmonton, Alta.; Department of Microbiology, Immunology and Infectious Diseases (Fonseca), Cumming School of Medicine, University of Calgary; Alberta Precision Laboratories Calgary (Fonseca), Alberta Health Services, Calgary, Alta.; National Microbiology Laboratory (Murphy), Public Health Agency of Canada; Alberta Precision Laboratories Edmonton (Murphy), Alberta Health Services, Edmonton, Alta.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Alberta Health Services (McDougall), Edmonton, Alta.
Eddy LangDepartments of Medicine (Ravani, Manns) and Community Health Sciences (Ravani, Manns), and O'Brien Institute for Public Health (Ravani, Manns), and Libin Cardiovascular Institute of Alberta (Ravani, Manns), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine, and Medical Microbiology and Immunology (Saxinger, Chandran), Faculty of Medicine and Dentistry, University of Alberta; Infection Prevention and Control (Chandran), Alberta Health Services, Edmonton, Alta.; Department of Microbiology, Immunology and Infectious Diseases (Fonseca), Cumming School of Medicine, University of Calgary; Alberta Precision Laboratories Calgary (Fonseca), Alberta Health Services, Calgary, Alta.; National Microbiology Laboratory (Murphy), Public Health Agency of Canada; Alberta Precision Laboratories Edmonton (Murphy), Alberta Health Services, Edmonton, Alta.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Alberta Health Services (McDougall), Edmonton, Alta.
Laura McDougallDepartments of Medicine (Ravani, Manns) and Community Health Sciences (Ravani, Manns), and O'Brien Institute for Public Health (Ravani, Manns), and Libin Cardiovascular Institute of Alberta (Ravani, Manns), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine, and Medical Microbiology and Immunology (Saxinger, Chandran), Faculty of Medicine and Dentistry, University of Alberta; Infection Prevention and Control (Chandran), Alberta Health Services, Edmonton, Alta.; Department of Microbiology, Immunology and Infectious Diseases (Fonseca), Cumming School of Medicine, University of Calgary; Alberta Precision Laboratories Calgary (Fonseca), Alberta Health Services, Calgary, Alta.; National Microbiology Laboratory (Murphy), Public Health Agency of Canada; Alberta Precision Laboratories Edmonton (Murphy), Alberta Health Services, Edmonton, Alta.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Alberta Health Services (McDougall), Edmonton, Alta.
Braden MannsDepartments of Medicine (Ravani, Manns) and Community Health Sciences (Ravani, Manns), and O'Brien Institute for Public Health (Ravani, Manns), and Libin Cardiovascular Institute of Alberta (Ravani, Manns), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Departments of Medicine, and Medical Microbiology and Immunology (Saxinger, Chandran), Faculty of Medicine and Dentistry, University of Alberta; Infection Prevention and Control (Chandran), Alberta Health Services, Edmonton, Alta.; Department of Microbiology, Immunology and Infectious Diseases (Fonseca), Cumming School of Medicine, University of Calgary; Alberta Precision Laboratories Calgary (Fonseca), Alberta Health Services, Calgary, Alta.; National Microbiology Laboratory (Murphy), Public Health Agency of Canada; Alberta Precision Laboratories Edmonton (Murphy), Alberta Health Services, Edmonton, Alta.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Alberta Health Services (McDougall), Edmonton, Alta.
University of Alberta · CAAlberta Health Services · CAUniversity of Calgary · CAPublic Health Agency of Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among asymptomatic patients admitted to hospital has implications for personal protective equipment use, testing strategy and confidence in the safety of acute care services. Our aim was to estimate the positivity rate of reverse transcription polymerase chain reaction (RT-PCR) testing among people admitted to hospital without symptoms of coronavirus disease 2019 (COVID-19) in Alberta, Canada.

methodsBetween Apr. 9 and May 24, 2020, we screened for COVID-19 symptoms and tested for SARS-CoV-2 infection in all consecutive adult patients (≥ 18 yr) admitted via emergency department to 3 Alberta hospitals. We summarized the parameters of the epidemic curve and assessed the performance of symptom screening versus RT-PCR results on nasopharyngeal or oropharyngeal swab samples.

resultsThe study period encompassed Alberta's initial epidemic curve, with peak active cases per 100 000 of 71.4 (0.07%) on Apr. 30, 2020, and 14.7 and 14.6 at the beginning (Apr. 9, 2020) and end (May 24, 2020), respectively. Testing for SARS-CoV-2 infection (64.9% throat and 35.1% nasopharyngeal swabs) was done on 3375 adults (mean age 51, standard deviation 21, yr; 51.5% men). None of the asymptomatic patients (

interpretationIn a region with low disease prevalence where protocolized symptom assessment was in place during the admission process, we did not identify people admitted to hospital without COVID-19 symptoms who were RT-PCR positive. There may not be additive benefit to universal testing of asymptomatic patients on hospital admission in a setting of low pretest probability and strong public health containment.

Indexed as

Quality ImprovementAlbertaAsymptomatic DiseasesClinical Laboratory TechniquesComorbidityCOVID-19Emergency Service, HospitalFemaleFollow-Up StudiesHumansMaleMass ScreeningMiddle AgedProspective StudiesSARS-CoV-2

Identifiers

PMID33355274
PMCPMC7759116
OpenAlexW3116242184

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.