Evidence map›Paper›PMID 33355119›Full record

ArticleBiology open2021

Wound-induced polyploidization is dependent on Integrin-Yki signaling.

Rose Besen-McNally, Kayla J Gjelsvik, Vicki P Losick

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Growth under pressure: The pros and cons of polyploidy induced by stress.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Cell cycle re-entry in the agingbioRxiv : the preprint server for biology · 2024
    Article
  8. Article
  9. Germline and Somatic Cell Syncytia in Insects.Results and problems in cell differentiation · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Polyploidy in Tissue Repair and Regeneration.Cold Spring Harbor perspectives in biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rose Besen-McNallyBiology Department, Boston College, Chestnut Hill, MA, 02467, USA.
Kayla J GjelsvikGraduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, 0×4469, USA.
Vicki P LosickBiology Department, Boston College, Chestnut Hill, MA, 02467, USA vicki.losick@bc.edu.ORCID 0000-0003-4608-2980
Boston College · USMount Desert Island Biological Laboratory · US

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
Understanding the role of thyroid hormone signaling during axolotl limb regenerationP20GM104318 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI DRUMMOND, IAIN A. · 2013 to 2023
$23.0M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
The Regulation of Polyploidy in Health and DiseaseR35GM124691 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Vicki P Losick · 2017 to 2026
$3.3M
NIGMS NIH HHS P20 GM103423NIGMS NIH HHS P20 GM104318NIGMS NIH HHS R01 GM084947NIGMS NIH HHS R35 GM124691NIH HHS P40 OD018537
6 · The paper itself

Abstract

A key step in tissue repair is to replace lost or damaged cells. This occurs via two strategies: restoring cell number through proliferation or increasing cell size through polyploidization. Studies in

Indexed as

PolyploidySignal TransductionWound HealingAnimalsDrosophilaDrosophila ProteinsEndoreduplicationFluorescent Antibody TechniqueFocal Adhesion Protein-Tyrosine KinasesGene Expression RegulationIntegrinsYAP-Signaling ProteinsDrosophila ProteinsFocal Adhesion Protein-Tyrosine KinasesIntegrinsYAP-Signaling ProteinsYki protein, DrosophilaDrosophilaFocal adhesion kinaseIntegrinPolyploidyWound healingYorkie

Identifiers

PMID33355119
PMCPMC7860123
OpenAlexW3116546081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.