Evidence map›Paper›PMID 33354758›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022

Diagnostic value of FDG PET/CT imaging in patients with surgically managed infective endocarditis: results of a retrospective analysis at a tertiary center.

Sabine Julia Maria Sag, Karin Menhart, Jirka Grosse, Florian Hitzenbichler, Frank Hanses, Arno Mohr, Bernd Salzberger, Matthäus Zerdzitzki, Michael Hilker, Leopold Rupprecht and 4 more

Abstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Infective endocarditis related abscess is an important complication and requires awareness on all imaging modalities.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  2. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  3. Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  4. Review
  5. Article
  6. Nuclear Imaging in Infective Endocarditis.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Sabine Julia Maria SagDepartment of Internal Medicine II, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Karin MenhartDepartment of Nuclear Medicine, University Hospital Regensburg, Regensburg, Germany.
Jirka GrosseDepartment of Nuclear Medicine, University Hospital Regensburg, Regensburg, Germany.
Florian HitzenbichlerDepartment of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.
Frank HansesDepartment of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.
Arno MohrDepartment of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.
Bernd SalzbergerDepartment of Infection Prevention and Infectious Diseases, University Hospital Regensburg, Regensburg, Germany.
Matthäus ZerdzitzkiDepartment of Cardiothoracic Surgery, University Hospital Regensburg, Regensburg, Germany.
Michael HilkerDepartment of Cardiothoracic Surgery, University Hospital Regensburg, Regensburg, Germany.
Leopold RupprechtDepartment of Cardiothoracic Surgery, University Hospital Regensburg, Regensburg, Germany.
Dirk HellwigDepartment of Nuclear Medicine, University Hospital Regensburg, Regensburg, Germany.
Christof SchmidDepartment of Cardiothoracic Surgery, University Hospital Regensburg, Regensburg, Germany.
Lars Siegfried MaierDepartment of Internal Medicine II, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Can Martin SagDepartment of Internal Medicine II, University Hospital Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany. can-martin.sag@ukr.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe assessed the diagnostic value of FDG PET/CT in a real-world cohort of patients with surgically managed infective endocarditis (IE).

methodsWe performed a retrospective analysis of all patients hospitalized in a tertiary IE referral medical center from January 2014 to October 2018 fulfilling the following criteria: ICD-10 code for IE and OPS code for both, heart surgery and FDG PET/CT.

resultsFinal analysis included 29 patients, whereof 28 patients had surgically proven IE. FDG PET/CT scan was true-positive in 15 patients (sensitivity (SEN) 56%) and false-negative in 12 patients. Combination of Duke criteria (DC) with FDG PET/CT scan resulted in gain of SEN for all patients with confirmed IE (SEN of DC 79% vs SEN of combination DC and FDG PET/CT 89%), driven by a relevant gain in PVE patients only (SEN of DC 78% vs SEN of combination DC and FDG PET/CT 94%). Interestingly, higher prosthesis age was observed in patients with false-negative scans.

conclusionsWe found a SEN of 56% for FDG PET/CT in a real-world cohort of patients with surgically proven IE which was associated with a 16% gain of IE diagnosis in patients with PVE when combined with DC.

Indexed as

EndocarditisEndocarditis, BacterialHeart Valve ProsthesisFluorodeoxyglucose F18HumansPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18Radiopharmaceuticalsimage interpretationInflammationPET

Identifiers

PMID33354758
PMCPMC9162977

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.