Evidence map›Paper›PMID 33354733›Full record

ArticleActa neurochirurgica2021

Consensus statement from the international consensus meeting on post-traumatic cranioplasty.

C Iaccarino, A Kolias, P D Adelson, A M Rubiano, E Viaroli, A Buki, G Cinalli, K Fountas, T Khan, S Signoretti and 36 more

Registry-linked trialAbstract readConference ProceedingsConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neurochirurgica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06776614 (A Comparative-effectiveness Study on Expansion Craniotomy Versus Decompressive Craniectomy for Surgical Management of Traumatic Brain Injury in Patients With Intracranial Compartment Syndrome), which is not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06776614 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Comparative-effectiveness Study on Expansion Craniotomy Versus Decompressive Craniectomy for Surgical Management of Traumatic Brain Injury in Patients With Intracranial Compartment Syndrome

Typeobservational_patient_registrySponsorMeditech FoundationRan2025 to 2027Enrolled292ConditionsTraumatic Brain Injuries, Intracranial HypertensionArmsDecompressive Craniectomy, Expansion Craniotomy
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Rehabilitation after diagnosis of hydrocephalus in severe acquired brain injury: the unmet need for evidence-based guidelines.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
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  7. Risk factors for postoperative fever following cranioplasty in children: a retrospective cohort analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors.

C IaccarinoDivision of Neurosurgery, Department of Biomedical, Metabolic and Neural Sciences, University Hospital of Modena, University of Modena and Reggio Emilia, Modena, Italy.
A KoliasDivision of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital, Cambridge Biomedical Campus, University of Cambridge, Box 167, Cambridge, CB2 0QQ, UK. ak721@cam.ac.uk.
P D AdelsonDivision of Neurosurgery/Children's Neuroscience, Department of Child Health, Barrow Neurological Institute, Phoenix Children's Hospital, Phoenix, AZ, USA.
A M RubianoNeurosciences Institute, Neurosurgery Service, MEDITECH-INUB Research Group, El Bosque Clinic, El Bosque University, Bogotá, Colombia.
E ViaroliDivision of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital, Cambridge Biomedical Campus, University of Cambridge, Box 167, Cambridge, CB2 0QQ, UK.
A BukiDepartment of Neurosurgery, Pecs University, Pecs, Hungary.
G CinalliDepartment of Neurosurgey, "Santobono-Posillipon" Children's Hospital, Naples, Italy.
K FountasDepartment of Neurosurgery, Universityof Thessaly, University Hospital of Larissa, Larissa, Greece.
T KhanNorthwest General Hospital and Medical Center, Peshawar, Pakistan.
S SignorettiDepartment of Neurosurgery, "Sant'Eugenio" Hospital - ASL ROMA 2, Rome, Italy.
V WaranNeurosurgery Division, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
A O AdeleyeDepartment of Neurological Surgery, University College Hospital, College of Medicine, University of Ibadan, Ibadan, Nigeria.
R AmorimDivision of Neurosurgery, University of São Paulo Medical School, São Paulo, SP, Brazil.
A BertuccioNeurosurgical Unit, "SS. Antonio e Biagio e Cesare Arrigo" Hospital, Alessandria, Italy.
A CamaDepartment of Pediatric Neurosurgery, Institute for Scientifict Research and Care "Giannina Gaslini", Genua, Italy.
R M ChesnutDepartment of Neurological Surgery, School of Global Health Harborview Medical Center, University of Washington, Seattle, WA, USA.
P De BonisDepartment of Neurosurgery, Sant'Anna University Hospital, Ferrara, Italy.
A EstraneoIRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.
A FigajiDivision of Neurosurgery, Neuroscience Institute, University of Cape Town, Red Cross Children's Hospital, Rondebosch, Cape Town, South Africa.
S I FlorianDepartment of Neurosurgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania.
R FormisanoPost-Coma Unit, IRCCS Santa Lucia Foundation, Rome, Italy.
P FrassanitoDepartment of Pediatric Neurosurgery, "University Cattolica del Sacro Cuore- School of Medicine "A. Gemelli", Rome, Italy.
C GatosDepartment of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Thessaly, Greece.
A GermanòNeurosurgical Clinic, Department of Neurosciences, University of Messina, Messina, Italy.
C GiussaniNeurosurgery, Department of Surgery and Translational Medicine, Milan Centre for Neuroscience, University of Milano-Bicocca, San Gerardo Hospital, Monza, Italy.
I HossainDepartment of Neurosurgery, Division of Clinical Neurosciences, University of Turku and Turku University Hospital, Turku, Finland.
P KasprzakDepartment of Neurosurgery, Medical University of Lodz, Łódź, Poland.
F La PortaNeurorehabilitation Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy.
D LindnerDepartment of Neurosurgery, University Hospital Leipzig, Leipzig, Germany.
A I R MaasDepartment of Neurosurgery, Antwerp University Hospital and University of Antwerp, Edegem, Belgium.
W PaivaDivision of Neurosurgery, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
P PalmaDepartment of Pediatric Neurosurgery, "Bambin Gesù" Children's Hospital, Rome, Italy.
K B ParkProgram for Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.
P PerettaDepartment of Pediatric Neurosurgery, "Città della Salute e della Scienza di Torino - Presidio ospedaliero Regina Margherita", Turin, Italy.
A PompucciDepartment of Neurosurgery, ASL Latina "Santa Maria Goretti" Hospital, Latina, Italy.
J PostiDepartment of Neurosurgery and Turku Brain Injury Centre, Turku University Hospital and University of Turku, Turku, Finland.
S K SenguptaDepartment of Neurosurgery, Command Hospital Kolkata, Kolkata, India.
A SinhaDepartment of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, UK.
V SinhaDepartment of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
R StefiniDepartiment of Neurosurgery, ASS T-Ovest Milanese, Legnano Hospital, Milan, Italy.
G TalamontiDepartment of Neurosurgery, "Niguarda" Hospital, Milan, Italy.
A TasiouDepartment of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Thessaly, Greece.
G ZonaDivision of Neurosurgery, Department of Neurosciences (DINOGMI), IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
M ZucchelliSection of Pediatric Neurosurgery, Institute for Scientifict Research and Care "Bellaria", Bologna, Italy.
P J HutchinsonDivision of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital, Cambridge Biomedical Campus, University of Cambridge, Box 167, Cambridge, CB2 0QQ, UK.
F ServadeiHumanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDue to the lack of high-quality evidence which has hindered the development of evidence-based guidelines, there is a need to provide general guidance on cranioplasty (CP) following traumatic brain injury (TBI), as well as identify areas of ongoing uncertainty via a consensus-based approach.

methodsThe international consensus meeting on post-traumatic CP was held during the International Conference on Recent Advances in Neurotraumatology (ICRAN), in Naples, Italy, in June 2018. This meeting was endorsed by the Neurotrauma Committee of the World Federation of Neurosurgical Societies (WFNS), the NIHR Global Health Research Group on Neurotrauma, and several other neurotrauma organizations. Discussions and voting were organized around 5 pre-specified themes: (1) indications and technique, (2) materials, (3) timing, (4) hydrocephalus, and (5) paediatric CP.

resultsThe participants discussed published evidence on each topic and proposed consensus statements, which were subject to ratification using anonymous real-time voting. Statements required an agreement threshold of more than 70% for inclusion in the final recommendations.

conclusionsThis document is the first set of practical consensus-based clinical recommendations on post-traumatic CP, focusing on timing, materials, complications, and surgical procedures. Future research directions are also presented.

Indexed as

Consensus Statements as TopicBrain Injuries, TraumaticCraniotomyHumansHydrocephalusItalyPlastic Surgery ProceduresCranioplastyDecompressive craniectomyhydrocephalusNeurosurgeryRehabilitation

Identifiers

PMID33354733
PMCPMC7815592

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.