ArticleiScience2021
Spatial clustering of orientation preference in primary visual cortex of the large rodent agouti.
Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- A column-like organization for ocular dominance in mouse visual cortex.Nature communications · 2025Article
- A unifying framework for functional organization in early and higher ventral visual cortex.Neuron · 2024Article
- A Unifying Principle for the Functional Organization of Visual Cortex.bioRxiv : the preprint server for biology · 2023Article
- Tuning instability of non-columnar neurons in the salt-and-pepper whisker map in somatosensory cortex.Nature communications · 2022Article
- Orientation pinwheels in primary visual cortex of a highly visual marsupial.Science advances · 2022Article
- The Organization of Somatostatin-Immunoreactive Cells in the Visual Cortex of the Gerbil.Biomedicines · 2022Article
- The large numbers of minicolumns in the primary visual cortex of humans, chimpanzees and gorillas are related to high visual acuity.Frontiers in neuroanatomy · 2022Article
- Editorial: Cortical Maps: Data and Models.Frontiers in neuroinformatics · 2022Article
- Characteristics of Whale Müller Glia in Primary and Immortalized Cultures.Frontiers in neuroscience · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
All rodents investigated so far possess orientation-selective neurons in the primary visual cortex (V1) but - in contrast to carnivores and primates - no evidence of periodic maps with pinwheel-like structures. Theoretical studies debating whether phylogeny or universal principles determine development of pinwheels point to V1 size as a critical constraint. Thus, we set out to study maps of agouti, a big diurnal rodent with a V1 size comparable to cats'. In electrophysiology, we detected interspersed orientation and direction-selective neurons with a bias for horizontal contours, corroborated by homogeneous activation in optical imaging. Compatible with spatial clustering at short distance, nearby neurons tended to exhibit similar orientation preference. Our results argue against V1 size as a key parameter in determining the presence of periodic orientation maps. They are consistent with a phylogenetic influence on the map layout and development, potentially reflecting distinct retinal traits or interspecies differences in cortical circuitry.
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