Evidence map›Paper›PMID 33354649›Full record

ArticleCollabra. Psychology2020

Is Healthy Neuroticism Associated with Health Behaviors? A Coordinated Integrative Data Analysis.

Eileen K Graham, Sara J Weston, Nicholas A Turiano, Damaris Aschwanden, Tom Booth, Fleur Harrison, Bryan D James, Nathan A Lewis, Steven R Makkar, Swantje Mueller and 25 more

Open access · goldAbstract read
In one paragraph

Article in Collabra. Psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
3.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Article
  6. Personality trait and state associations with cognitive functioning and variability in middle-aged and older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  7. The virtue of temperance: a neurobiological perspective.Frontiers in human neuroscience · 2026
    Article
  8. Interplay between insomnia, anxiety, and depression.World journal of psychiatry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 18 institutions in 5 countries.

Eileen K GrahamNorthwestern University, Department of Medical Social Sciences, Chicago, IL, USA.
Sara J WestonUniversity of Oregon, Department of Psychology, Eugene, OR, USA.
Nicholas A TurianoWest Virginia University, Department of Psychology and the West Virginia Prevention Research Center, Morgantown, WV, USA.
Damaris AschwandenFlorida State University, Department of Geriatrics, Tallahassee, FL, USA.
Tom BoothUniversity of Edinburgh, Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, Edinburgh, Scotland.
Fleur HarrisonUniversity of New South Wales, Centre for Healthy Brain Aging, Sydney NSW, Australia.
Bryan D JamesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Nathan A LewisUniversity of Victoria, Department of Psychology, Victoria, BC, Canada.
Steven R MakkarUniversity of New South Wales, Centre for Healthy Brain Aging, Sydney NSW, Australia.
Swantje MuellerUniversity of Hamburg, Berlin Germany, Department of Psychology.
Kristi M WisniewskiUniversity of Southern California, Leonard Davis School of Gerontology, Los Angeles, CA.
Tomiko YonedaUniversity of Victoria, Department of Psychology, Victoria, BC, Canada.
Ruixue ZhaoyangPennsylvania State University, Center for Healthy Aging, State College, PA, USA.
Avron SpiroVA Boston Healthcare System, Boston, MA, USA.
Sherry WillisUniversity of Washington, Department of Psychiatry and Behavioral Sciences, Seattle, WA, USA.
K Warner SchaiePennsylvania State University, Department of Human Development and Psychology, State College, PA, USA.
Martin SliwinskiPennsylvania State University, Center for Healthy Aging, State College, PA, USA.
Richard A LiptonAlbert Einstein College of Medicine, Bronx, NY, USA.
Mindy J KatzAlbert Einstein College of Medicine, Bronx, NY, USA.
Ian J DearyUniversity of Edinburgh, Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, Edinburgh, Scotland.
Elizabeth M ZelinskiUniversity of Southern California, Leonard Davis School of Gerontology, Los Angeles, CA.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Perminder S SachdevUniversity of New South Wales, Centre for Healthy Brain Aging, Sydney NSW, Australia.
Henry BrodatyUniversity of New South Wales, Centre for Healthy Brain Aging, Sydney NSW, Australia.
Julian N TrollorUniversity of New South Wales, Centre for Healthy Brain Aging, Sydney NSW, Australia.
David AmesUniversity of Melbourne Academic Unit for Psychiatry of Old Age and National Ageing Research Institute, Kew & Parkville, Australia.
Margaret J WrightUniversity of Queensland, Queensland Brain Institute, Australia.
Denis GerstorfHumboldt University, Berlin Germany, Department of Psychology.
Mathias AllemandUniversity of Zurich, Department of Psychology, Zurich, Switzerland.
Johanna DreweliesHumboldt University, Berlin Germany, Department of Psychology.
Gert G WagnerGermany Institue for Economic Research, Berlin Germany.
Graciela Muniz-TerreraUniveristy of Edinburgh, Centre for Dementia Prevention, Edinburgh, Scotland.
Andrea M PiccininUniversity of Victoria, Department of Psychology, Victoria, BC, Canada.
Scott M HoferUniversity of Victoria, Department of Psychology, Victoria, BC, Canada.
Daniel K MroczekNorthwestern University, Department of Medical Social Sciences, Chicago, IL, USA.
UNSW Sydney · AUUniversity of Houston - Victoria · USPennsylvania State University · USAlbert Einstein College of Medicine · USAlzheimer Scotland · GBNorthwestern University · USRush University Medical Center · USUniversity of Southern California · USBoston University · USFlorida State University · USNational Ageing Research Institute · AUUniversität Hamburg · DEUniversity of Edinburgh · GBUniversity of Oregon · USUniversity of Queensland · AUUniversity of Washington · USUniversity of Zurich · CHWest Virginia University · US

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CAROL D. RYFF · 2016 to 2026
$74.8M
Vascular Structure and Function in Cognitive AgingP01AG003949 · NIA · YESHIVA UNIVERSITY · PI CAROL A. DERBY · 1985 to 2026
$73.9M
SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI SCHNEIDER, JULIE A. · 1991 to 2020
$49.1M
EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
RISK FACTORS, PATHOLOGY, AND CLINICAL EXPRESSIONS OF ADR01AG015819 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1998 to 2024
$21.4M
RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
Study Coordination and Measurement CoreP01AG043362 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI HOFER, SCOTT M. · 2013 to 2017
$7.8M
PERSONALITY AND WELL BEING TRAJECTORIES IN ADULTHOODR01AG018436 · NIA · PURDUE UNIVERSITY WEST LAFAYETTE · PI MROCZEK, DANIEL K. · 2000 to 2020
$6.7M
LONGITUDINAL ASSESSMENT OF COGNITION IN ADULTSR01AG010569 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZELINSKI, ELIZABETH M · 1993 to 2011
$4.2M
Boston Early Adversity and Mortality Study (BEAMS): Linking Administrative Data to Long-Term Longitudinal StudiesRF1AG064006 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEE, LEWINA ONYI, MROCZEK, DANIEL K. · 2019 to 2023
$3.8M
Personality prediction of dementia risk and progressionR01AG067622 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MROCZEK, DANIEL K. · 2019 to 2023
$3.2M
Long-term Effects of ACTIVE Cognitive Training on Everyday Functioning and Dementia-related Outcomes: Association of Race and Social Determinants of HealthR01AG056486 · NIA · UNIVERSITY OF WASHINGTON · PI REBOK, GEORGE W., WILLIS, SHERRY L · 2017 to 2020
$3.1M
Medical Research Council G0700704Medical Research Council MR/K026992/1NIA NIH HHS K01 AG050823NIA NIH HHS P01 AG003949NIA NIH HHS P01 AG043362NIA NIH HHS P30 AG010161NIA NIH HHS R01 AG010569NIA NIH HHS R01 AG015819NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG018436NIA NIH HHS R01 AG032037NIA NIH HHS R01 AG055653NIA NIH HHS R01 AG056486NIA NIH HHS R01 AG067622NIA NIH HHS RF1 AG064006NIA NIH HHS T32 AG000037NIA NIH HHS U19 AG051426
6 · The paper itself

Abstract

Current literature suggests that neuroticism is positively associated with maladaptive life choices, likelihood of disease, and mortality. However, recent research has identified circumstances under which neuroticism is associated with positive outcomes. The current project examined whether "healthy neuroticism", defined as the interaction of neuroticism and conscientiousness, was associated with the following health behaviors: smoking, alcohol consumption, and physical activity. Using a pre-registered multi-study coordinated integrative data analysis (IDA) approach, we investigated whether "healthy neuroticism" predicted the odds of engaging in each of the aforementioned activities. Each study estimated identical models, using the same covariates and data transformations, enabling optimal comparability of results. These results were then meta-analyzed in order to estimate an average (N-weighted) effect and to ascertain the extent of heterogeneity in the effects. Overall, these results suggest that neuroticism alone was not related to health behaviors, while individuals higher in conscientiousness were less likely to be smokers or drinkers, and more likely to engage in physical activity. In terms of the healthy neuroticism interaction of neuroticism and conscientiousness, significant interactions for smoking and physical activity suggest that the association between neuroticism and health behaviors was smaller among those high in conscientiousness. These findings lend credence to the idea that healthy neuroticism may be linked to certain health behaviors and that these effects are generalizable across several heterogeneous samples.

Indexed as

Big FiveCoordinated IDAHealth BehaviorsHealthy NeuroticismIALSA

Identifiers

PMID33354649
PMCPMC7751766
OpenAlexW3045409934

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.