Evidence map›Paper›PMID 33354648›Full record

ArticleCollabra. Psychology2020

Is Healthy Neuroticism Associated with Longevity? A Coordinated Integrative Data Analysis.

Nicholas A Turiano, Eileen K Graham, Sara J Weston, Tom Booth, Fleur Harrison, Bryan D James, Nathan A Lewis, Steven R Makkar, Swantje Mueller, Kristi M Wisniewski and 20 more

Open access · goldAbstract read
In one paragraph

Article in Collabra. Psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Personality trait and state associations with cognitive functioning and variability in middle-aged and older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. A Coordinated Data Analysis of Four Studies Exploring Age Differences in Social Interactions and Loneliness During a Global Pandemic.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Internalizing psychopathology and all-cause mortality: a comparison of transdiagnostic vs. diagnosis-based risk prediction.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021
    Article
  14. Article
  15. Associations Between Personality Traits and Cognitive Resilience in Older Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 17 institutions in 4 countries.

Nicholas A TurianoWest Virginia University, Department of Psychology and the West Virginia Prevention Research Center, Morgantown, WV, USA.
Eileen K GrahamNorthwestern University, Department of Medical Social Sciences, Chicago, IL, USA.
Sara J WestonUniversity of Oregon, Department of Psychology, Eugene, OR, USA.
Tom BoothCentre for Cognitive Aging and Cognitive Epidemiology, Department of Psychology The University of Edinburgh, Edinburgh, Scotland.
Fleur HarrisonThe University of New South Wales, Centre for Healthy Brain Ageing (CHeBA), Sydney NSW, Australia.
Bryan D JamesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Nathan A LewisThe University of Victoria, Department of Psychology, Victoria, BC, Canada.
Steven R MakkarThe University of New South Wales, Centre for Healthy Brain Ageing (CHeBA), Sydney NSW, Australia.
Swantje MuellerHamburg University, Berlin, Germany, Department of Psychology, Berlin, Germany.
Kristi M WisniewskiUniversity of Southern California, Department of Gerontology, Los Angeles, CA, USA.
Ruixue ZhaoyangCenter for Healthy Aging, Pennsylvania State University, State College, PA, USA.
Avron SpiroVA Boston Healthcare System, Boston, MA, USA.
Sherry WillisUniversity of Washington, Department of Psychiatry and Behavioral Sciences, Seattle, WA, USA.
K Warner SchaiePennsylvania State University, Department of Human Development and Psychology, State College, PA, USA.
Richard B LiptonAlbert Einstein College of Medicine, Bronx, NY, USA.
Mindy KatzAlbert Einstein College of Medicine, Bronx, NY, USA.
Martin SliwinskiCenter for Healthy Aging, Pennsylvania State University, State College, PA, USA.
Ian J DearyUniversity of New South Wales, Department of Developmental Disability Neuropsychiatry, Sydney, Australia.
Elizabeth M ZelinskiUniversity of Southern California, Department of Gerontology, Los Angeles, CA, USA.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
Perminder S SachdevThe University of New South Wales, Centre for Healthy Brain Ageing (CHeBA), Sydney NSW, Australia.
Henry BrodatyThe University of New South Wales, Centre for Healthy Brain Ageing (CHeBA), Sydney NSW, Australia.
Julian N TrollorThe University of New South Wales, Centre for Healthy Brain Ageing (CHeBA), Sydney NSW, Australia.
David AmesUniversity of Melbourne Academic Unit for Psychiatry of Old Age and National Ageing Research Institute, Kew & Parkville, Australia.
Margaret J WrightUniversity of Queensland, Queensland Brain Institute, Australia.
Denis GerstorfHumboldt University Berlin, Germany, Department of Psychology, Berlin, Germany.
Graciela Muniz-TerreraUniversity of Edinburgh, Centre for Dementia Prevention, Edinburgh, Scotland.
Andrea M PiccininThe University of Victoria, Department of Psychology, Victoria, BC, Canada.
Scott M HoferThe University of Victoria, Department of Psychology, Victoria, BC, Canada.
Daniel K MroczekNorthwestern University, Department of Medical Social Sciences, Chicago, IL, USA.
UNSW Sydney · AUPennsylvania State University · USUniversity of Houston - Victoria · USAlbert Einstein College of Medicine · USRush University Medical Center · USUniversity of Southern California · USAlzheimer Scotland · GBBehavioral Tech Research, Inc. · USBoston University · USHumboldt State University · USMidwestern University · USNorthwestern University · USUniversity of Edinburgh · GBUniversity of Melbourne · AUUniversity of Oregon · USUniversity of Queensland · AUWest Virginia University · US

Funding

U19 MIDlife in the United States-Diversity Supplement-WellsU19AG051426 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER L COE · 2016 to 2026
$74.8M
Vascular Structure and Function in Cognitive AgingP01AG003949 · NIA · YESHIVA UNIVERSITY · PI STEVEN SUEY-MING CHIN · 1985 to 2026
$73.9M
SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1991 to 2020
$49.1M
EPIDEMIOLOGY OF NEURAL RESERVE AND NEUROBIOLOGY IN AGINGR01AG017917 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 2001 to 2023
$43.3M
RISK FACTORS, PATHOLOGY, AND CLINICAL EXPRESSIONS OF ADR01AG015819 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BENNETT, DAVID ALAN · 1998 to 2024
$21.4M
RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
Study Coordination and Measurement CoreP01AG043362 · NIA · OREGON HEALTH & SCIENCE UNIVERSITY · PI HOFER, SCOTT M. · 2013 to 2017
$7.8M
LONGITUDINAL ASSESSMENT OF COGNITION IN ADULTSR01AG010569 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZELINSKI, ELIZABETH M · 1993 to 2011
$4.2M
Boston Early Adversity and Mortality Study (BEAMS): Linking Administrative Data to Long-Term Longitudinal StudiesRF1AG064006 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEE, LEWINA ONYI, MROCZEK, DANIEL K. · 2019 to 2023
$3.8M
Personality prediction of dementia risk and progressionR01AG067622 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MROCZEK, DANIEL K. · 2019 to 2023
$3.2M
Long-term Effects of ACTIVE Cognitive Training on Everyday Functioning and Dementia-related Outcomes: Association of Race and Social Determinants of HealthR01AG056486 · NIA · UNIVERSITY OF WASHINGTON · PI REBOK, GEORGE W., WILLIS, SHERRY L · 2017 to 2020
$3.1M
Seattle Longitudinal Study: Archiving, Harmonizing and Augmenting Alzheimer's Disease Relevant Data SetsR01AG055653 · NIA · UNIVERSITY OF WASHINGTON · PI TOGA, ARTHUR W, WILLIS, SHERRY L · 2017 to 2020
$1.8M
Medical Research Council G0700704Medical Research Council MR/K026992/1NIA NIH HHS K01 AG050823NIA NIH HHS P01 AG003949NIA NIH HHS P01 AG043362NIA NIH HHS P30 AG010161NIA NIH HHS R01 AG010569NIA NIH HHS R01 AG015819NIA NIH HHS R01 AG017917NIA NIH HHS R01 AG032037NIA NIH HHS R01 AG055653NIA NIH HHS R01 AG056486NIA NIH HHS R01 AG067622NIA NIH HHS RF1 AG064006NIA NIH HHS T32 AG000037NIA NIH HHS U19 AG051426
6 · The paper itself

Abstract

Individual differences in the Big Five personality traits have emerged as predictors of health and longevity. Although there are robust protective effects for higher levels of conscientiousness, results are mixed for other personality traits. In particular, higher levels of neuroticism have significantly predicted an increased risk of mortality, no-risk at all, and even a reduced risk of dying. The current study hypothesizes that one potential reason for the discrepancy in these findings for neuroticism is that interactions among neuroticism and other key personality traits have largely been ignored. Thus, in the current study we focus on testing whether the personality traits neuroticism and conscientiousness interact to predict mortality. Specifically, we borrow from recent evidence of "healthy neuroticism" to explore whether higher levels of neuroticism are only a risk factor for increased mortality risk when conscientiousness levels are low. We conducted a pre-registered integrative data analysis using 12 different cohort studies (total

Indexed as

Big Fiveconscientiousnesscoordinated IDAhealthy neuroticismIALSAmortality

Identifiers

PMID33354648
PMCPMC7751763
OpenAlexW3044369015

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.