Evidence map›Paper›PMID 33354576›Full record

ArticleJournal of diabetes research2020

Tangeretin Inhibition of High-Glucose-Induced IL-1

Dong Qin, Yan-Rong Jiang

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Ethyl Acetate Fractions ofInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Identifying Active Compounds and Mechanisms ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Dong QinHenan Eye Institute, Henan Provincial Eye Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.ORCID https://orcid.org/0000-0003-0494-0270
Yan-Rong JiangDepartment of Ophthalmology, People's Hospital, Peking University, Beijing, China.
Peking University · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tangeretin, a natural compound extracted from citrus plants, has been reported to have antiproliferative, antidiabetic, anti-invasive, and antioxidant properties. However, the role of tangeretin in diabetic retinopathy (DR) is unknown. In the present study, we investigated whether tangeretin had any effect on the expression of interleukin 1 beta (IL-1

Indexed as

Cell LineDiabetic RetinopathyFlavonesGlucoseHumansInterleukin-1betaInterleukin-6PhosphorylationProto-Oncogene Proteins c-aktRetinal Pigment EpitheliumSignal TransductionTransforming Growth Factor beta1Vascular Endothelial Growth Factor AFlavonesGlucoseIL1B protein, humanIL6 protein, humanInterleukin-1betaInterleukin-6Proto-Oncogene Proteins c-akttangeretinTGFB1 protein, humanTransforming Growth Factor beta1Vascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID33354576
PMCPMC7737452
OpenAlexW3112541725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.