Evidence map›Paper›PMID 33354567›Full record

ArticleBioMed research international2020

Relative Telomere Length in Peripheral Blood Cells and Hypertension Risk among Mine Workers: A Case-Control Study in Chinese Coal Miners.

Sheng-Nan Yu, Shi-Qi Chen, Guo-Quan Fan, Wei-Zhe Pan, Jin Jia, Qian Wang, Li Ma, Ben Li, Mei Qiang, Yu-Lan Qiu and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Sheng-Nan Yu *Department of Toxicology, School of Public Health, Shanxi Medical University, Taiyuan, China.
Shi-Qi Chen *Department of Toxicology, School of Public Health, Shanxi Medical University, Taiyuan, China.
Guo-Quan FanDepartment of Immunology, School of Basic Medical, Shanxi Medical University, Taiyuan, China.
Wei-Zhe PanDepartment of Toxicology, School of Public Health, Shanxi Medical University, Taiyuan, China.
Jin JiaDepartment of Toxicology, School of Public Health, Shanxi Medical University, Taiyuan, China.
Qian WangDepartment of Toxicology, School of Public Health, Shanxi Medical University, Taiyuan, China.
Li MaDepartment of Toxicology, School of Public Health, Shanxi Medical University, Taiyuan, China.
Ben LiDepartment of Toxicology, School of Public Health, Shanxi Medical University, Taiyuan, China.
Mei QiangDepartment of Child and Adolescent Health, School of Public Health, Shanxi Medical University, Taiyuan, China.
Yu-Lan QiuDepartment of Toxicology, School of Public Health, Shanxi Medical University, Taiyuan, China.ORCID https://orcid.org/0000-0001-6334-9662
Tong WangDepartment of Statistics, School of Public Health, Shanxi Medical University, Taiyuan, China.ORCID https://orcid.org/0000-0002-9403-7167
Shanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is a common chronic disease in middle-aged and elderly people and is an important risk factor for many cardiovascular diseases. Its pathogenesis remains unclear. Epidemiological studies have found that the loss of telomere length in peripheral blood cells can increase the risk of coronary heart disease, myocardial infarction, and other diseases. However, a correlation between loss of telomere length and hypertension has not been established. In this study, we aimed to explore the association between telomere length and the risk of essential hypertension (EH) in Chinese coal miners. A case-control study was performed with 215 EH patients and 222 healthy controls in a large coal mining group located in North China. Face-to-face interviews were conducted by trained staff with the necessary medical knowledge. Relative telomere length (RTL) was measured by a quantitative real-time PCR assay using DNA extracted from peripheral blood. In the control group, the age-adjusted RTL was statistically significantly lower in miners performing hard physical labour compared with nonphysical labour (

Indexed as

Coal MiningMinersOccupational ExposureAdultCase-Control StudiesChinaEssential HypertensionFemaleHumansHypertensionMaleMiddle AgedReal-Time Polymerase Chain ReactionRegression AnalysisRetrospective StudiesRisk Factors

Identifiers

PMID33354567
PMCPMC7735841
OpenAlexW3110985127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.