Evidence map›Paper›PMID 33354503›Full record

ArticleActa pharmaceutica Sinica. B2020

Targeting castration-resistant prostate cancer with a novel ROR

Jianwei Zheng, Junfeng Wang, Qian Wang, Hongye Zou, Hong Wang, Zhenhua Zhang, Jianghe Chen, Qianqian Wang, Panxia Wang, Yueshan Zhao and 10 more

Open access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 2 institutions in 2 countries.

Jianwei ZhengSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Junfeng WangCAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Qian WangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Hongye ZouDepartment of Biochemistry and Molecular Medicine, UC Davis Comprehensive Cancer Center, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.
Hong WangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Zhenhua ZhangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Jianghe ChenSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Qianqian WangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Panxia WangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Yueshan ZhaoSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Jing LuSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Xiaolei ZhangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Songtao XiangDepartment of Urology, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Haibin WangDepartment of Joint Orthopaedic, the First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Jinping LeiSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Hong-Wu ChenDepartment of Biochemistry and Molecular Medicine, UC Davis Comprehensive Cancer Center, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA.
Peiqing LiuSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Yonghong LiuCAS Key Laboratory of Tropical Marine Bio-resources and Ecology/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Fanghai HanDepartment of Gastrointestinal Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Junjian WangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Sun Yat-sen University · CNGuangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) patients who progress to metastatic castration-resistant PCa (mCRPC) mostly have poor outcomes due to the lack of effective therapies. Our recent study established the orphan nuclear receptor ROR

Indexed as

AntagonistCastration-resistant prostate cancerElaiophylinNuclear receptorRORγ

Identifiers

PMID33354503
PMCPMC7745055
OpenAlexW3040698466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.