Evidence map›Paper›PMID 33354338›Full record

ArticleObesity science & practice2020

Does sexual functioning improve with migraine improvements and/or weight loss?-A post hoc analysis in the Women's Health and Migraine (WHAM) trial.

Leah Schumacher, Rena Wing, J Graham Thomas, Jelena Pavlovic, Kathleen Digre, Samantha Farris, Kristine Steffen, David Sarwer, Dale Bond

Open access · goldAbstract read
In one paragraph

Article in Obesity science & practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Leah SchumacherDepartment of Psychiatry and Human Behavior Alpert Medical School of Brown University/The Miriam Hospital, Weight Control and Diabetes Research Center Providence Rhode Island USA.ORCID https://orcid.org/0000-0003-1557-4659
Rena WingDepartment of Psychiatry and Human Behavior Alpert Medical School of Brown University/The Miriam Hospital, Weight Control and Diabetes Research Center Providence Rhode Island USA.
J Graham ThomasDepartment of Psychiatry and Human Behavior Alpert Medical School of Brown University/The Miriam Hospital, Weight Control and Diabetes Research Center Providence Rhode Island USA.ORCID https://orcid.org/0000-0001-7549-2431
Jelena PavlovicDepartment of Neurology and the Montefiore Headache Center Albert Einstein College of Medicine/Montefiore Medical Center Bronx New York USA.
Kathleen DigreDepartment of Neurology University of Utah Health Sciences Center Salt Lake City Utah USA.
Samantha FarrisDepartment of Psychology, Rutgers The State University of New Jersey Piscataway New Jersey USA.
Kristine SteffenDepartment of Pharmaceutical Sciences North Dakota State University Fargo North Dakota USA.
David SarwerCenter for Obesity Research and Education, College of Public Health Temple University Philadelphia Pennsylvania USA.
Dale BondDepartment of Psychiatry and Human Behavior Alpert Medical School of Brown University/The Miriam Hospital, Weight Control and Diabetes Research Center Providence Rhode Island USA.
Brown University · USAlbert Einstein College of Medicine · USNeuropsychiatric Research Institute · USRutgers, The State University of New Jersey · USTemple University · USUniversity of Utah · US

Funding

Training in Behavioral & Preventive MedicineT32HL076134 · NHLBI · MIRIAM HOSPITAL · PI John Graham Thomas · 2006 to 2026
$5.7M
Behavioral Weight Loss as a Treatment for Migraine in Obese WomenR01NS077925 · NINDS · MIRIAM HOSPITAL · PI BOND, DALE S · 2012 to 2015
$2.1M
NHLBI NIH HHS T32 HL076134NINDS NIH HHS R01 NS077925
6 · The paper itself

Abstract

backgroundDespite plausibility of migraine headaches contributing to impaired sexual function among women, data are inconsistent and point to obesity as a potential confounder. Prospective studies that assess the relative importance of migraine improvements and weight loss in relation to sexual function could help elucidate associations among migraine, obesity and female sexual dysfunction (FSD).

objectiveTo evaluate sexual function changes and predictors of improvement after behavioural weight loss (BWL) intervention for migraine or migraine education (ME).

methodsWomen with migraine and overweight/obesity were randomized to 16 weeks of BWL (

resultsAmong treatment completers (

conclusionSexual functioning did not improve with either BWL or ME despite migraine headache improvements in both conditions and weight loss after BWL. However, weight loss related to improvements in physiological components of the sexual response (i.e., arousal) and overall sexual functioning, whereas reduced headache frequency related to improved sexual satisfaction. Additional research with larger samples is needed.

Indexed as

female sexual dysfunctionmigraineobesitywomen's health

Identifiers

PMID33354338
PMCPMC7746968
OpenAlexW3044977229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.