ArticlePulmonary circulation
Heart rate monitoring improves clinical assessment during 6-min walk.
Article in Pulmonary circulation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Sensor for sports applications: monitoring and assessment of intrinsic capacity enhancement in older adults during brisk walking.Frontiers in public health · 2025Pooled it
- Rodatristat ethyl decreases activity in pulmonary arterial hypertension: results from the ELEVATE-2 trial.Annals of the American Thoracic Society · 2026Trial
- Relationship Between Right Ventricular Function and Chronotropic Incompetence in Pulmonary Arterial Hypertension Associated With Connective Tissue Disease.CHEST pulmonary · 2026Article
- When Good Biology Meets Negative Clinical Trials: Lessons from PHANTOM and EDIPHY.Annals of the American Thoracic Society · 2026Article
- 3-ERJ open research · 2026Article
- Functional recovery after pulmonary embolism: A pilot study using metabolic monitoring during the 6-minute walk test.Respiratory medicine · 2026Observational
- Longitudinal Remote 6-Minute Walk Distance and Cardiac Effort Using Wearable Sensors in Pulmonary Hypertension.Pulmonary circulation · 2026Article
- Supplemental Oxygen Decreases Cardiac Effort in Pulmonary Arterial Hypertension.Pulmonary circulation · 2026Article
- Heart Rate Variability in Pulmonary Arterial Hypertension.Pulmonary circulation · 2025Article
- Electronically delivered rehabilitation after acute pulmonary embolism is safe and improves quality of life.The European respiratory journal · 2024Article
- Motor and Respiratory Tele-Rehabilitation in Patients with Long COVID-19 after Hospital Discharge: An Interventional Study.Life (Basel, Switzerland) · 2024Article
- Inertial Measurement Unit and Heart Rate Monitoring to Assess Cardiovascular Fitness of Manual Wheelchair Users during the Six-Minute Push Test.Sensors (Basel, Switzerland) · 2024Article
- Cardiac effort and 6-min walk distance correlate with stroke volume measured by cardiac magnetic resonance imaging.Pulmonary circulation · 2024Article
- Peak steps: Capacity for activity improves after adding approved therapy in pulmonary arterial hypertension.Pulmonary circulation · 2023Article
- Cardiac Effort to Compare Clinic and Remote 6-Minute Walk Testing in Pulmonary Arterial Hypertension.Chest · 2022Observational
- Comparison of chest- and wrist-based actigraphy in pulmonary arterial hypertension.European heart journal. Digital health · 2022Article
- TORREY, a Phase 2 study to evaluate the efficacy and safety of inhaled seralutinib for the treatment of pulmonary arterial hypertension.Pulmonary circulationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Right ventricular (RV) function is a predictor of outcomes in pulmonary arterial hypertension (PAH). The 6-min walk test (6MWT) is likely an indirect measure of RV function during exercise, but changes in absolute walk distance can also be influenced by factors like effort and musculoskeletal disease. Paired 6MWT with continuous electrocardiogram monitoring was performed in stable PAH patients, patients adding PAH therapies, and healthy controls. Heart rate expenditure (HRE) was calculated (integrating pulse during 6MWT) and then divided by walk distance (HRE/d). We also evaluated changes in peak heart rate, time above age-adjusted maximum predicted heart rate, and heart rate at 6 min. HRE/d was compared to invasive hemodynamic measures in patients who had right heart catheterization performed within seven days, WHO functional class assessment, and Emphasis 10 questionnaire. We measured two 6MWT in 15 stable PAH patients, 13 treatment intensification patients, and 8 healthy controls. HRE/d was reproducible in the stable PAH group (median difference, -0.79%), while it decreased (median difference, 23%,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.