Evidence map›Paper›PMID 33354306›Full record

ArticleRare tumors2020

Spindle cell carcinoma of the breast managed with neoadjuvant AIM: A case report.

April Choi, Philip M Carpenter, Shefali Chopra, Kristi M Lara, William W Tseng, Dakshesh B Patel, James Hu

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Rare tumors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

April ChoiDepartment of Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0001-7980-886X
Philip M CarpenterDepartment of Pathology, Keck School of Medicine at USC, Los Angeles, CA, USA.
Shefali ChopraDepartment of Pathology, Keck School of Medicine at USC, Los Angeles, CA, USA.
Kristi M LaraDepartment of Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA.
William W TsengDepartment of Surgery, Division of Breast, Endocrine and Soft Tissue Surgery, Keck School of Medicine at USC, Los Angeles, CA, USA.
Dakshesh B PatelDepartment of Radiology, Keck School of Medicine at USC, Los Angeles, CA, USA.
James HuDepartment of Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-0620-4664
Keck Hospital of USC · USUSC Norris Comprehensive Cancer Center · USLAC+USC Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spindle cell carcinoma (SpC), also known as metaplastic carcinoma-spindle cell type, is a subtype of metaplastic carcinoma. Metaplastic carcinomas of the breast are rare but are thought to be more aggressive than invasive ductal carcinomas. Due to their rarity, there are few randomized trials that can inform any standardized approaches to treatment. Treatment is instead extrapolated from other types of breast cancer or metaplastic carcinomas of different locations. Here we present the first known case report of a patient with spindle cell carcinoma of the breast successfully treated with a standard sarcoma neoadjuvant regimen of doxorubicin, ifosfamide, and mesna (AIM) that resulted in >99% necrosis of the tumor and negative margins at the time of resection.

Indexed as

AIMBreast carcinomadoxorubicinifosfamidemetaplasticneoadjuvantspindle cell

Identifiers

PMID33354306
PMCPMC7734559
OpenAlexW3111040076

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.