Evidence map›Paper›PMID 33354251›Full record

ArticleRevue francaise d'allergologie (2009)2021

[Impact of confinement on the follow-up of oral immunotherapies: A multicentre study in the Île-de-France region].

C Le-Thai, T Guiddir, R Stern, M Smilov, J-C Pigeot, A Merzouk, C Billard-Larue, A-C de Menibus, A Nemni

Open access · greenAbstract readEnglish Abstract
In one paragraph

Article in Revue francaise d'allergologie (2009), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Psychological impacts of coronavirus disease 2019 on people with asthma, allergic rhinitis, and food allergy.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

C Le-ThaiUnité d'allergologie enfants-adultes, centre hospitalier intercommunal Robert-Ballanger, boulevard Robert-Ballanger, 93600 Aulnay-sous-Bois, France.
T GuiddirService de pédiatrie générale, centre hospitalier universitaire Bicêtre, 78, avenue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France.
R SternUnité d'allergologie enfants-adultes, centre hospitalier intercommunal Robert-Ballanger, boulevard Robert-Ballanger, 93600 Aulnay-sous-Bois, France.
M SmilovUnité d'allergologie enfants-adultes, centre hospitalier intercommunal Robert-Ballanger, boulevard Robert-Ballanger, 93600 Aulnay-sous-Bois, France.
J-C PigeotUnité d'allergologie enfants-adultes, centre hospitalier intercommunal Robert-Ballanger, boulevard Robert-Ballanger, 93600 Aulnay-sous-Bois, France.
A MerzoukUnité d'allergologie enfants-adultes, centre hospitalier intercommunal Robert-Ballanger, boulevard Robert-Ballanger, 93600 Aulnay-sous-Bois, France.
C Billard-LarueUnité d'allergologie enfants-adultes, grand hôpital de l'Est Francilien - site de Meaux, 6, rue Saint-Fiacre, 77100 Meaux, France.
A-C de MenibusUnité d'allergologie enfants-adultes, centre hospitalier intercommunal Robert-Ballanger, boulevard Robert-Ballanger, 93600 Aulnay-sous-Bois, France.
A NemniUnité d'allergologie enfants-adultes, centre hospitalier intercommunal Robert-Ballanger, boulevard Robert-Ballanger, 93600 Aulnay-sous-Bois, France.
Centre hospitalier Robert-Ballanger · FRHôpital d'Enfants · FRBicêtre Hospital · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of the studySeveral studies have confirmed the impact of confinement on the population, resulting in disruption of care, somatic and psychological effects. Our study looks at adverse effects and problems of adherence to oral immunotherapy therapy (OIT) during this period. PATIENTS AND

methodsA total of 132 patients, mostly children (95%), with an atopic history (60%) followed for an OIT were included in 3 allergology centers in Île-de-France, during the period of confinement from 03/16 to 05/11/20. The main food allergens used for OIT were peanut (38%), cow's milk (24%), hazelnut (14%), egg (9%), cashew nut and pistachio nut (8%).

resultsAdverse effects were found in 13 patients or 10% of the cases. These reactions were mainly grade 1 and 2 according to the Ring and Messmer classification. Three patients had grade 3 reactions and six patients used epinephrine at home. Adherence was correct in 81% of cases with no omissions. Three patients increased their daily dose without medical advice. No significant difference was found in the subgroup analysis comparing age-matched children followed up in OIT in 2019 and 2020 over the same period in the same hospital.

conclusionThere was no increase in adverse events in OIT during the confinement period. Therapeutic education during OIT is paramount and helps to reduce the occurrence of adverse events.

Indexed as

AdherenceAdverse eventsConfinementCOVID-19Food allergyOral immunotherapyTherapeutic education

Identifiers

PMID33354251
PMCPMC7746089
OpenAlexW3196874603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.