Evidence map›Paper›PMID 33354118›Full record

ArticleNoro psikiyatri arsivi2020

Assessment of IL-7RA T244I Polymorphism as a Risk Factor of Multiple Sclerosis in Turkish Population.

Miraç Aysen Ünsal, Nüket Yıldız Manukyan, Nihal IŞik, Güher Saruhan Dİreskenelİ

Open access · greenAbstract read
In one paragraph

Article in Noro psikiyatri arsivi, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Miraç Aysen ÜnsalNeurology Department, Sultan Abdülhamid Han Training Hospital, İstanbul, Turkey.
Nüket Yıldız ManukyanNeurology Department, Fatih Sultan Mehmet Training Hospital, İstanbul, Turkey.
Nihal IŞikNeurology Department, Okan University School of Medicine, İstanbul, Turkey.
Güher Saruhan DİreskenelİPhysiology Department, İstanbul University School of Medicine, İstanbul, Turkey.
Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi · TRIstanbul University · TROkan University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe T244I variant of the IL-7RA gene, rs6897932, is one of the first polymorphisms found to be associated with the development of multiple sclerosis (MS). Although several studies provided evidence for the association of MS and this variant, other studies could not confirm this result. These inconsistent results suggest that the role of this polymorphism in the development of disease is associated with ethnicity.

methodsWe investigated rs6897932 polymorphisms in a large cohort of patients with MS and healthy controls in a turkish population.

resultsIn our study, there were no significant differences in genotype frequencies in the IL-7RA rs6897932 polymorphism and no significant difference between C and T alleles in patients with MS and controls.

conclusionThis study is the first to evaluate the risk of the rs6897932 polymorphism in turkish patients with MS.

Indexed as

IL-7RA genemultiple sclerosisrs6897932

Identifiers

PMID33354118
PMCPMC7735144
OpenAlexW2906502571

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.