ReviewCurrent issues in molecular biology2021
Lyme Disease Pathogenesis.
Open access · goldAbstract readReview
In one paragraph
Review in Current issues in molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 92 citations in OpenAlex.
- Mostly getting along -Borrelia burgdorferi and its manipulation of the host immune system.ImmunoHorizons · 2026Review
- Metabolomics of cerebrospinal fluid in pediatric neuroborreliosis: unraveling candidate immunometabolic signatures and diagnostic potential.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Riboflavin Salvage Supports Glycolysis in Borrelia burgdorferi Through Flavin-Dependent NADMolecular microbiology · 2026Article
- Bactofilins are essential spatial organizers of peptidoglycan insertion in the Lyme disease spirocheteJournal of bacteriology · 2026Article
- Article
- Complement inhibition by a unique cluster of immunomodulatory outer surface proteins of Borrelia recurrentis.Nature communications · 2026Article
- Spatial modeling of Borrelia genospecies in human-biting ticks from the French citizen science programme CiTIQUE.Scientific reports · 2026Article
- TheInfection and immunity · 2026Article
- Infection-Triggered Immune Dysregulation and Immunopathology in Lyme Disease: Mechanisms and Clinical Implications.Journal of clinical medicine · 2026Review
- A Pre-Clinical Model of Synovitis Using Ex vivo Human Synovial Tissue with Preserved Function and Architecture.Journal of visualized experiments : JoVE · 2026Article
- Natural genetic variation impacts complement inhibitory activity of PFam54 orthologs of Asian Borrelia bavariensis.Scientific reports · 2026Article
- Making the best of a sticky situation: Infection-mediated endothelial activation promotes new interactions with adhesins of the host-adapted Lyme disease spirochete.bioRxiv : the preprint server for biology · 2026Article
- Multiplexed single-tier immunoassay for improved Lyme disease diagnosis across all disease stages.Research square · 2026Article
- Characterizing the impact of intracutaneous dissemination on host responses duringFrontiers in immunology · 2026Article
- In vitro and in vivo endothelial interactions of Leptospira species are markers of virulence.PLoS neglected tropical diseases · 2026Article
- Peptidoglycan architecture dictates protein interactions, tissue tropism, and arthritis in the Lyme disease spirochete Borrelia burgdorferi.PLoS pathogens · 2026Article
- From forest floor to doctor's office: the immunological journey ofFrontiers in immunology · 2026Review
- The wild, wild west of plasmids: First insights into comparative genomics of Borrelia burgdorferi sensu lato.PloS one · 2026Article
- Evaluation of Immune Response Dynamics: Analyzing the Parameters of Complete Blood Count (CBC) in Experimental Borreliosis.Life (Basel, Switzerland) · 2025Article
- Mechanisms of bacterial host-to-host transmission.Microbiology and molecular biology reviews : MMBR · 2025Review
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 2 countries.
Jenifer CoburnCenter For Infectious Disease Research, Medical College of Wisconsin, 8701 Watertown Plank Rd., TBRC C3980, Milwaukee, WI 53226, USA.
Brandon GarciaDepartment of Microbiology and Immunology, East Carolina University, Brody School of Medicine, Greenville, NC 27858, USA.
Linden T HuDepartment of Molecular Biology and Microbiology, Vice Dean of Research, Tufts University School of Medicine, 136 Harrison Ave., Boston, MA 02111, USA.
Mollie W JewettImmunity and Pathogenesis Division Head, Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, 6900 Lake Nona Blvd. Orlando, FL 32827, USA.
Peter KraiczyInstitute of Medical Microbiology and Infection Control, University Hospital Frankfurt, Goethe University Frankfurt, Paul-Ehrlich-Str. 40, 60596 Frankfurt, Germany.
Steven J NorrisDepartment of Pathology and Laboratory Medicine, University of Texas Medical School at Houston, P.O. Box 20708, Houston, TX 77225, USA.
Jon SkareProfessor and Associate Head, Texas A and M University, 8447 Riverside Pkwy, Bryan, TX 77807, USA.
East Carolina University · USMedical College of Wisconsin · USTexas A&M University · USTufts University · USUniversity Hospital Frankfurt · DEUniversity of Central Florida · US
Funding
VIRULENCE-ASSOCIATED PROTEINS IN LYME DISEASER01AI037277 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NORRIS, STEVEN J. · 1995 to 2015
$5.4MVirulence Determinants of Borrelia burgdorferiR01AI059048 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NORRIS, STEVEN J. · 2004 to 2016
$5.3MDetermination of the genetic basis for B. burgdorferi mammalian infectivityR01AI099094 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI Mollie W Jewett · 2013 to 2026
$4.0MVirulence Mechanisms of Multifunctional Borrelial ProteinsR01AI146930 · NIAID · KANSAS STATE UNIVERSITY · PI GARCIA, BRANDON LEE · 2020 to 2024
$3.6MCoping with Stress: Next Generation Approaches to Borrelia burgdorferi Host AdaptationR01AI131656 · NIAID · TUFTS UNIVERSITY BOSTON · PI HU, LINDEN T, SKARE, JON T · 2017 to 2021
$3.3MFunctional Analyses of Borrelia burgdorferi AdhesinsR01AI118799 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI CHACONAS, GEORGE, COBURN, JENIFER L · 2016 to 2020
$3.3MMultiple B. burgdorferi Factors Collaborate to Evade Complement-Mediated DefensesR01AI121401 · NIAID · TUFTS UNIVERSITY BOSTON · PI COBURN, JENIFER L, LEONG, JOHN M · 2016 to 2020
$3.1MRole of human innate immune mutations in loss of tolerance to Borrelia burgdorferiR01AI150157 · NIAID · TUFTS UNIVERSITY BOSTON · PI HU, LINDEN T · 2020 to 2024
$3.0MIdentification of protective Lyme disease antigens using live attenuated vaccinesR01AI121217 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI COBURN, JENIFER L, NARDELLI, DEAN · 2016 to 2020
$1.9MVirulence Mechanisms of Multifunctional Borrelial ProteinsR56AI146930 · NIAID · EAST CAROLINA UNIVERSITY · PI GARCIA, BRANDON LEE, SKARE, JON T · 2019 to 2019
$617kRole of carbon availability in environmental adaptation by Borrelia burgdorferiR21AI111317 · NIAID · TUFTS UNIVERSITY BOSTON · PI HU, LINDEN T, LIN, TAO · 2015 to 2016
$475kClassical Complement Pathway Evasion Mechanisms of Lyme Disease SpirochetesR21AI133367 · NIAID · KANSAS STATE UNIVERSITY · PI GARCIA, BRANDON LEE, SKARE, JON T · 2017 to 2018
$435kNIAID NIH HHS K22 AI081730NIAID NIH HHS R01 AI037277NIAID NIH HHS R01 AI059048NIAID NIH HHS R01 AI099094NIAID NIH HHS R01 AI118799NIAID NIH HHS R01 AI121217NIAID NIH HHS R01 AI121401NIAID NIH HHS R01 AI131656NIAID NIH HHS R01 AI146930NIAID NIH HHS R01 AI150157NIAID NIH HHS R21 AI103905NIAID NIH HHS R21 AI111317NIAID NIH HHS R21 AI119821NIAID NIH HHS R21 AI133367NIAID NIH HHS R21 AI140510NIAID NIH HHS R56 AI146930NINDS NIH HHS R21 NS102766NINDS NIH HHS R21 NS104767
Abstract
Lyme disease
Indexed as
BorreliaDisease SusceptibilityAnimalsArthropod VectorsDisease Models, AnimalGene Expression Regulation, BacterialHost-Pathogen InteractionsHumansLyme DiseaseTicksVirulenceVirulence FactorsVirulence Factors
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.