Evidence map›Paper›PMID 33353500›Full record

ArticleJournal of biomolecular structure & dynamics2022

Identification of potential non-nucleoside MraY inhibitors for tuberculosis chemotherapy using structure-based virtual screening.

Pankaj Pandey, Shamba Chatterjee, Tomayo Berida, Robert J Doerksen, Sudeshna Roy

Open access · greenAbstract read
In one paragraph

Article in Journal of biomolecular structure & dynamics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pankaj PandeyDepartment of BioMolecular Sciences, Division of Medicinal Chemistry, University of Mississippi, University, MS, USA.ORCID 0000-0001-9128-8254
Shamba ChatterjeeDepartment of BioMolecular Sciences, Division of Medicinal Chemistry, University of Mississippi, University, MS, USA.ORCID 0000-0003-1415-6981
Tomayo BeridaDepartment of BioMolecular Sciences, Division of Medicinal Chemistry, University of Mississippi, University, MS, USA.ORCID 0000-0002-3578-1033
Robert J DoerksenDepartment of BioMolecular Sciences, Division of Medicinal Chemistry, University of Mississippi, University, MS, USA.
Sudeshna RoyDepartment of BioMolecular Sciences, Division of Medicinal Chemistry, University of Mississippi, University, MS, USA.
University of Mississippi · US

Funding

Target-based chemotherapeutics development against Mycobacterium tuberculosisR21AI142210 · NIAID · UNIVERSITY OF MISSISSIPPI · PI ROY, SUDESHNA · 2019 to 2020
$411k
Laser spectroscopic instrumentation for isotopic sensing of biogenic Nitric OxideR21GM103460 · NIGMS · PRINCETON UNIVERSITY · PI WYSOCKI, GERARD · 2012 to 2012
$190k
RENOVATION OF FOURTH FLOOR OF FASER HALLC06RR014503 · NCRR · UNIVERSITY OF MISSISSIPPI · PI WELLS, BARBARA G · 1999 to 1999
–
NCRR NIH HHS C06 RR014503NIAID NIH HHS R21 AI142210NIGMS NIH HHS R21 GM103460
6 · The paper itself

Abstract

The efforts to limit the spread of the tuberculosis epidemic have been challenged by the rise of drug-resistant strains of

Indexed as

Mycobacterium tuberculosisTuberculosisAntitubercular AgentsHumansLigandsMolecular Docking SimulationMolecular Dynamics SimulationAntitubercular AgentsLigandsdockinghomology modelingmolecular dynamicsMraYtuberculosisvirtual screening

Identifiers

PMID33353500
PMCPMC9948644
OpenAlexW3116747438

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.