Evidence map›Paper›PMID 33353285›Full record

ArticleHaematologica2021

Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC).

John N Brewin, Helen Rooks, Kate Gardner, Harry Senior, Mrinmayi Morje, Hamel Patel, David Calvet, Pablo Bartolucci, Swee-Lay Thein, Stephan Menzel and 1 more

Open access · goldAbstract readLetter
In one paragraph

Article in Haematologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

John N BrewinKings College London, UK; Kings College Hospital, London. John.brewin@kcl.ac.uk.
Helen RooksKings College London.
Kate GardnerKings College London, UK; Guys and St Thomas Hospital, London.
Harry SeniorKings College London.
Mrinmayi MorjeKings College London.
Hamel PatelKings College London.
David CalvetHenri Mondor Hopital, Paris.
Pablo BartolucciHenri Mondor Hopital, Paris.
Swee-Lay TheinNIH, Bethesda.
Stephan MenzelKings College London.
David C ReesKings College London, UK; Kings College Hospital, London.
King's College - North Carolina · USHôpitaux Universitaires Henri-Mondor · FRKing's College London · GBNational Institutes of Health · USSt. Thomas Hospital · CA

Funding

Medical Research Council MR/T013389/1
6 · The paper itself

Abstract

Not available.

Indexed as

Anemia, Sickle CellHemoglobin SC DiseaseCerebral InfarctionGenome-Wide Association StudyHemoglobin, SickleHumansHemoglobin, Sickle

Identifiers

PMID33353285
PMCPMC8168512
OpenAlexW3114964641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.