Evidence map›Paper›PMID 33353118›Full record

ArticleInternational journal of molecular sciences2020

Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-

Marta Szandruk-Bender, Benita Wiatrak, Łukasz Szczukowski, Piotr Świątek, Maria Rutkowska, Stanisław Dzimira, Anna Merwid-Ląd, Maciej Danielewski, Adam Szeląg

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-Pharmaceuticals (Basel, Switzerland) · 2025
    Article
  4. Sanguinarine-Chelerythrine fromPharmaceutics · 2025
    Article
  5. Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2025
    Article
  6. Article
  7. Pyridazinone: Current Progress in Synthesis of its Derivatives and Biological Activity.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Review
  8. Anti-Inflammatory and Antioxidant Pyrrolo[3,4-International journal of molecular sciences · 2024
    Article
  9. Article
  10. Interactions ofMembranes · 2023
    Article
  11. Article
  12. NewInternational journal of molecular sciences · 2021
    Article
  13. Novel 1,3,4-Oxadiazole Derivatives of Pyrrolo[3,4-Journal of inflammation research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marta Szandruk-BenderDepartment of Pharmacology, Faculty of Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.ORCID 0000-0002-4571-9452
Benita WiatrakDepartment of Pharmacology, Faculty of Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.ORCID 0000-0002-1404-2274
Łukasz SzczukowskiDepartment of Chemistry of Drugs, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.ORCID 0000-0002-9768-6269
Piotr ŚwiątekDepartment of Chemistry of Drugs, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wrocław, Poland.ORCID 0000-0003-4613-025X
Maria RutkowskaDepartment of Pharmacology, Faculty of Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.
Stanisław DzimiraDepartment of Pathology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Norwida 31, 50-375 Wrocław, Poland.ORCID 0000-0001-7203-2392
Anna Merwid-LądDepartment of Pharmacology, Faculty of Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.
Maciej DanielewskiDepartment of Pharmacology, Faculty of Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.ORCID 0000-0002-2671-5747
Adam SzelągDepartment of Pharmacology, Faculty of Medicine, Wroclaw Medical University, Mikulicza-Radeckiego 2, 50-345 Wrocław, Poland.ORCID 0000-0001-8104-5267
Wroclaw Medical University · PLWrocław University of Environmental and Life Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the availability of the current drug arsenal for pain management, there is still a clinical need to identify new, more effective, and safer analgesics. Based on our earlier study, newly synthesized 1,3,4-oxadiazole derivatives of pyrrolo[3,4-

Indexed as

AnalgesicsAnimalsDinoprostoneGastric MucosaMaleNociceptionNociceptive PainOxadiazolesPain MeasurementPeroxidasePyridazinesPyrrolesRatsRats, Wistar1,3,4-oxadiazoleAnalgesicsDinoprostoneOxadiazolesPeroxidasePyridazinesPyrrolespyrrolo(3,4-d)pyridazinone1,3,4-oxadiazoleformalin testpainpyrrolo[3,4-d]pyridazinonetail-flick test

Identifiers

PMID33353118
PMCPMC7766312
OpenAlexW3112177962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.