Evidence map›Paper›PMID 33353054›Full record

ArticleBiology2020

Effects of Propranolol on Growth, Lipids and Energy Metabolism and Oxidative Stress Response of

Bernardo Duarte, Eduardo Feijão, Ricardo Cruz de Carvalho, Irina A Duarte, Marisa Silva, Ana Rita Matos, Maria Teresa Cabrita, Sara C Novais, Marco F L Lemos, João Carlos Marques and 3 more

Open access · goldAbstract read
In one paragraph

Article in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  12. Frontiers in microbiology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Bernardo DuarteMARE-Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.ORCID 0000-0003-1914-7435
Eduardo FeijãoMARE-Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.ORCID 0000-0002-7109-7925
Ricardo Cruz de CarvalhoMARE-Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.ORCID 0000-0003-4612-9013
Irina A DuarteMARE-Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.
Marisa SilvaMARE-Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.ORCID 0000-0003-0626-3269
Ana Rita MatosDepartamento de Biologia Vegetal, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.ORCID 0000-0002-3495-2195
Maria Teresa CabritaCentro de Estudos Geográficos (CEG), Instituto de Geografia e Ordenamento do Território (IGOT), Universidade de Lisboa, Rua Branca Edmée Marques, 1600-276 Lisbon, Portugal.ORCID 0000-0002-4323-4945
Sara C NovaisMARE-Marine and Environmental Sciences Centre, ESTM, Politécnico de Leiria, 2520-641 Peniche, Portugal.
Marco F L LemosMARE-Marine and Environmental Sciences Centre, ESTM, Politécnico de Leiria, 2520-641 Peniche, Portugal.ORCID 0000-0001-9887-1864
João Carlos MarquesMARE-Marine and Environmental Sciences Centre, Department of Life Sciences, University of Coimbra, 3000 Coimbra, Portugal.
Isabel CaçadorMARE-Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.
Patrick Reis-SantosMARE-Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.ORCID 0000-0001-9843-9465
Vanessa F FonsecaMARE-Marine and Environmental Sciences Centre, Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisbon, Portugal.ORCID 0000-0002-6374-1194
University of Lisbon · PTInstituto Politécnico de Leiria · PTUniversity of Coimbra · PT

Funding

Fundação para a Ciência e a Tecnologia PTDC/MAR-EST/3048/2014 (BIOPHARMA), PTDC/CTA-AMB/30056/2017 (OPTOX), UIDB/04292/2020, UID/MULTI/04046/2019, CEECIND/00511/2017, DL57/2016/CP1479/CT0024, SFRH/BPD/95784/2013 and SFRH/BD/138376/2018
6 · The paper itself

Abstract

Present demographic trends suggest a rise in the contributions of human pharmaceuticals into coastal ecosystems, underpinning an increasing demand to evaluate the ecotoxicological effects and implications of drug residues in marine risk assessments. Propranolol, a non-selective β-adrenoceptor blocker, is used worldwide to treat high blood pressure conditions and other related cardiovascular conditions. Although diatoms lack β-adrenoceptors, this microalgal group presents receptor-like kinases and proteins with a functional analogy to the animal receptors and that can be targeted by propranolol. In the present work, the authors evaluated the effect of this non-selective β-adrenoceptor blocker in diatom cells using

Indexed as

energy metabolismpharmatoxicologyphotobiologyprimary producerstoxicophenomics

Identifiers

PMID33353054
PMCPMC7766914
OpenAlexW3111840796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.