Evidence map›Paper›PMID 33352991›Full record

ArticleLife (Basel, Switzerland)2020

Screening, Linkage to Care and Treatment of Hepatitis C Infection in Primary Care Setting in the South of Italy.

Anna Citarella, Simona Cammarota, Francesca F Bernardi, Carmine Coppola, Maria D'Antò, Marianna Fogliasecca, Elio Giusto, Mario Masarone, Angelo Salomone Megna, Carmine Sellitto and 6 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Evaluation of the hepatitis c virus screening program in the Marche Region (Italy): experience from the Pesaro-Urbino health authority.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Beyond Risk Factors: Rethinking Hepatitis B and Hepatitis C Screening in Primary Care.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Anna CitarellaLinkHealth Health Economics, Outcomes & Epidemiology s.r.l., 80143 Naples, Italy.
Simona CammarotaLinkHealth Health Economics, Outcomes & Epidemiology s.r.l., 80143 Naples, Italy.
Francesca F BernardiGeneral Direction of Health Care & Regional Health System Coordination, Drug & Device Politics, Campania Region, 80143 Naples, Italy.
Carmine CoppolaHepatology Unit, Department of Internal Medicine, Gragnano Hospital, 80054 Naples, Italy.
Maria D'AntòHepatology Unit, Department of Internal Medicine, Santa Maria delle Grazie Hospital, 80078 Naples, Italy.
Marianna FogliaseccaLinkHealth Health Economics, Outcomes & Epidemiology s.r.l., 80143 Naples, Italy.
Elio Giusto"Cooperativa Moscati" Medical Association, 07017 Salerno, Italy.
Mario MasaroneInternal Medicine and Hepatology Unit, Department of Medicine and Surgery, University of Salerno, 84084 Salerno, Italy.ORCID 0000-0003-0550-8201
Angelo Salomone MegnaAORN San Pio, Rummo Hospital, 82100 Benevento, Italy.
Carmine SellittoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84084 Salerno, Italy.ORCID 0000-0002-5595-7841
Rosa Servodio"Samnium Medica" Soc. Cooperative, 82100 Benevento, Italy.
Massimo Smaldone"Progetto Leonardo" Medical Association, 80078 Naples, Italy.
Laura StaianoHepatology Unit, Department of Internal Medicine, Gragnano Hospital, 80054 Naples, Italy.
Ugo TramaGeneral Direction of Health Care & Regional Health System Coordination, Drug & Device Politics, Campania Region, 80143 Naples, Italy.
Valeria ContiDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84084 Salerno, Italy.
Marcello PersicoInternal Medicine and Hepatology Unit, Department of Medicine and Surgery, University of Salerno, 84084 Salerno, Italy.
University of Salerno · ITCTO Hospital · ITRegione Campania · ITAzienda Ospedaliera G.Rummo · ITAzienda Ospedaliera S.Giuseppe Moscati · ITOspedale Santa Maria · ITSamnium Medica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus (HCV) infection remains a pressing public health issue. Our aim is to assess the linkage to care of patients with HCV diagnosis and to support the proactive case-finding of new HCV-infected patients in an Italian primary care setting. This was a retrospective cohort study of 44 general practitioners (GPs) who managed 63,955 inhabitants in the Campania region. Adults with already known HCV diagnosis or those with HCV high-risk profile at June 2019 were identified and reviewed by GPs to identify newly diagnosed of HCV and to assess the linkage to care and treatment for the HCV patients. Overall, 698 HCV patients were identified, 596 with already known HCV diagnosis and 102 identified by testing the high-risk group (2614 subjects). The 38.8% were already treated with direct-acting antivirals, 18.9% were referred to the specialist center and 42.3% were not sent to specialist care for treatment. Similar proportions were found for patients with an already known HCV diagnosis and those newly diagnosed. Given that the HCV infection is often silent, case-finding needs to be proactive and based on risk information. Our findings suggested that there needs to be greater outreach, awareness and education among GPs in order to enhance HCV testing, linkage to care and treatment.

Indexed as

barriersdirect acting antiviralseradicationprimary careproactive case-finding

Identifiers

PMID33352991
PMCPMC7766029
OpenAlexW3117864805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.