Evidence map›Paper›PMID 33352972›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Improved Cell Selectivity of Pseudin-2 via Substitution in the Leucine-Zipper Motif: In Vitro and In Vivo Antifungal Activity.

Seong-Cheol Park, Heabin Kim, Jin-Young Kim, Hyeonseok Kim, Gang-Won Cheong, Jung Ro Lee, Mi-Kyeong Jang

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Antimicrobial Peptides: An Update on Classifications and Databases.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Seong-Cheol ParkDepartment of Polymer Science and Engineering, Sunchon National University, Suncheon 57922, Korea.
Heabin KimDepartment of Polymer Science and Engineering, Sunchon National University, Suncheon 57922, Korea.
Jin-Young KimDepartment of Polymer Science and Engineering, Sunchon National University, Suncheon 57922, Korea.
Hyeonseok KimDepartment of Polymer Science and Engineering, Sunchon National University, Suncheon 57922, Korea.
Gang-Won CheongDivision of Applied Life Sciences and Research Institute of Natural Science, Gyeongsang National University, Jinju 52828, Korea.
Jung Ro LeeNational Institute of Ecology, 1210 Geumgang-ro, Maseo-myeon, Seocheon-gun 33657, Korea.ORCID 0000-0002-9596-3330
Mi-Kyeong JangDepartment of Polymer Science and Engineering, Sunchon National University, Suncheon 57922, Korea.
Sunchon National University · KRGyeongsang National University · KRNational Institute of Ecology · KR

Funding

National Institute of Ecology NIE-A-2020-07 and NIE-A-2020-10National Research Foundation of Korea NRF-2020R1A2C1013069
6 · The paper itself

Abstract

Several antimicrobial peptides (AMPs) have been discovered, developed, and purified from natural sources and peptide engineering; however, the clinical applications of these AMPs are limited owing to their lack of abundance and side effects related to cytotoxicity, immunogenicity, and hemolytic activity. Accordingly, to improve cell selectivity for pseudin-2, an AMP from

Indexed as

antifungal actionantimicrobial peptidecell selectivityleucine-zipper motif

Identifiers

PMID33352972
PMCPMC7766124
OpenAlexW3112815357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.