Evidence map›Paper›PMID 33352920›Full record

Trial reportNutrients2020

Vitamin D Supplementation Improves the Effects of the Rehabilitation Program on Balance and Pressure Distribution in Patients after Anterior Cervical Interbody Fusion-Randomized Control Trial.

Wojciech Skrobot, Ewelina Perzanowska, Katarzyna Krasowska, Damian J Flis, Katarzyna P Dzik, Wojciech Kloc, Jan Jacek Kaczor, Jędrzej Antosiewicz

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Observational
  4. Article
  5. The Role of Preoperative Vitamin D in Spine Surgery.Current reviews in musculoskeletal medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Wojciech SkrobotDepartment of Functional Diagnostics and Kinesiology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0002-7133-5970
Ewelina PerzanowskaDepartment of Functional Diagnostics and Kinesiology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0001-7698-5166
Katarzyna KrasowskaDepartment of Functional Diagnostics and Kinesiology, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Damian J FlisDepartment of Physiology and Biochemistry, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0002-6176-4536
Katarzyna P DzikDepartment of Physiology and Biochemistry, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0001-5414-7479
Wojciech KlocDepartment of Neurosurgery, Copernicus Hospital, 80-803 Gdansk, Poland.
Jan Jacek KaczorDepartment of Physiology and Biochemistry, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.ORCID 0000-0002-6370-2160
Jędrzej AntosiewiczDepartment of Bioenergetics and Physiology of Exercise, Medical University of Gdansk, 80-211 Gdansk, Poland.ORCID 0000-0002-7871-6469
Gdansk University of Physical Education and Sport · PLCopernicus Memorial Hospital · PLGdańsk Medical University · PL

Funding

Narodowe Centrum Nauki NCN UMO-2012/05/B/NZ7/02493
6 · The paper itself

Abstract

STUDY

designA double-blinded, randomized controlled trial.

backgroundSurgery is effective in reducing pain intensity in patients with cervical disc disease. However, functional measurements demonstrated that the results have been not satisfactory enough. Thus, rehabilitation programs combined with the supplementation of vitamin D could play an essential role.

methodsThe study recruited 30 patients, aged 20 to 70 years, selected for anterior cervical interbody fusion (ACIF). The patients were randomly divided into the placebo (Pl) and vitamin D (3200 IU D3/day) supplemented groups. The functional tests limits of stability (LOS), risk of falls (RFT), postural stability (PST), Romberg test, and foot pressure distribution were performed before supplementation (BS-week 0), five weeks after supplementation (AS-week 5), four weeks after surgery (BSVR-week 9), and 10 weeks after supervising rehabilitation (ASVR-week 19).

resultsThe concentration of 25(OH)D3 in the serum, after five weeks of supplementation, was significantly increased, while the Pl group maintained the same. The RFT was significantly reduced after five weeks of vitamin D supplementation. Moreover, a further significant decrease was observed following rehabilitation. In the Pl group, no changes in the RFT were observed. The overall postural stability index (OSI), LOS, and the outcomes of the Romberg test significantly improved in both groups; however, the effects on the OSI were more pronounced in the D3 group at the end of the rehabilitation program.

conclusionsOur data suggest that vitamin D supplementation positively affected the rehabilitation program in patients implemented four weeks after ACIF by reducing the risk of falls and improving postural stability.

Indexed as

Accidental FallsAdultAgedAnalysis of VarianceCalcifediolCervical VertebraeDouble-Blind MethodFemaleFootHumansMaleMiddle AgedPlacebosPostural BalancePressureSpinal FusionCalcifediolPlacebosVitamin DVitaminsACIFbalancecervical stabilizationlimits of stabilitypostural stabilityrisk of fallsRomberg testvitamin D supplementation

Identifiers

PMID33352920
PMCPMC7766157
OpenAlexW3111491578

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.