ReviewPathogens (Basel, Switzerland)2020
Current Developments in the Epidemiology and Control of Enzootic Bovine Leukosis as Caused by Bovine Leukemia Virus.
Review in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 69 citations in OpenAlex.
- Article
- Evaluation of bovine leukaemia virus infection control measures in Japanese Black beef cattle breeding farms: A 7-year longitudinal study based on proviral load.Veterinary record open · 2026Article
- Genetic Diversity of the BLVPathogens (Basel, Switzerland) · 2026Article
- Establishment and Characterization of Human Cell Lines Stably Infected With Bovine Leukemia Virus In Vitro Reveals Apoptosis After Latency and Silencing.Transboundary and emerging diseases · 2026Article
- First Identification ofPathogens (Basel, Switzerland) · 2025Article
- The Complexity of Bovine Leukemia Virus Oncogenesis.Viruses · 2025Review
- BLV coinfection impairs immunity and diagnostics in bovine tuberculosis.Scientific reports · 2025Article
- Development and application of a quantitative polymerase chain reaction assay for the detection and genotyping of bovine leukemia virus in cattle from Kazakhstan.Veterinary world · 2025Article
- Article
- Bovine Leukemia Virus: Origin, Prevalence, Phylogenetic Diversity, Risk Factors, and Strategies for Control.Animals : an open access journal from MDPI · 2025Review
- Serological and Molecular Evidence of Bovine Leukemia Virus in Sheep Populations in the South of Iran.Veterinary medicine and science · 2025Article
- Performance of 5 commercial ELISA kits for the detection of antibody to bovine leukemia virus.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2025Article
- OASIS evaluation of the French laboratory diagnostic surveillance system: right people, right techniques but imperfect use.Frontiers in veterinary science · 2025Article
- Metabolic Fingerprinting of Blood and Urine of Dairy Cows Affected by Bovine Leukemia Virus: A Mass Spectrometry Approach.Metabolites · 2024Article
- Reduction of antisense transcription affects bovine leukemia virus replication and oncogenesis.PLoS pathogens · 2024Article
- The influence of risk factors on bovine leukemia virus infection and proviral load in egyptian cattle.Veterinary research communications · 2024Article
- The Global Epidemiology of Bovine Leukemia Virus: Current Trends and Future Implications.Animals : an open access journal from MDPI · 2024Review
- Bovine leukemia virus transmission rates in persistent lymphocytotic infected dairy cows.Frontiers in veterinary science · 2024Article
- An immunoinformatics study reveals a new BoLA-DR-restricted CD4+ T cell epitopes on the Gag protein of bovine leukemia virus.Scientific reports · 2023Article
- Usefulness of Next-Generation Sequencing in Excluding Bovine Leukemia Virus as a Cause of Adult Camel Leukosis in Dromedaries.Pathogens (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Enzootic Bovine Leukosis (EBL) caused by the bovine leukemia virus (BLV) has been eradicated in over 20 countries. In contrast, the U.S. and many other nations are experiencing increasing prevalence in the absence of efforts to control transmission. Recent studies have shown that BLV infection in dairy cattle has a greater impact beyond the long-recognized lymphoma development that occurs in <5% of infected cattle. Like other retroviruses, BLV appears to cause multiple immune system disruptions, affecting both cellular and humoral immunity, which are likely responsible for increasingly documented associations with decreased dairy production and decreased productive lifespan. Realization of these economic losses has increased interest in controlling BLV using technology that was unavailable decades ago, when many nations eradicated BLV via traditional antibody testing and slaughter methods. This traditional control is not economically feasible for many nations where the average herd antibody prevalence is rapidly approaching 50%. The ELISA screening of cattle with follow-up testing via qPCR for proviral load helps prioritize the most infectious cattle for segregation or culling. The efficacy of this approach has been demonstrated in at least four herds. Breeding cattle for resistance to BLV disease progression also appears to hold promise, and several laboratories are working on BLV vaccines. There are many research priorities for a wide variety of disciplines, especially including the need to investigate the reports linking BLV and human breast cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.