Evidence map›Paper›PMID 33352849›Full record

ArticleJournal of clinical medicine2020

The Retinal Vessel Density as a New Vascular Biomarker in Multisystem Involvement in Fabry Disease: An Optical Coherence Tomography Angiography Study.

Gilda Cennamo, Daniela Montorio, Ciro Santoro, Sirio Cocozza, Letizia Spinelli, Teodolinda Di Risi, Eleonora Riccio, Camilla Russo, Giuseppe Pontillo, Roberta Esposito and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Gilda CennamoEye Clinic, Public Health Department, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0003-4253-1929
Daniela MontorioDepartment of Neurosciences, Reproductive Sciences and Dentistry, University of Naples "Federico II", 80131 Naples, Italy.ORCID 0000-0003-1423-9621
Ciro SantoroDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0002-6329-1680
Sirio CocozzaDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Letizia SpinelliDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Teodolinda Di RisiCEINGE-Advanced Biotechnologies, 80145 Naples, Italy.
Eleonora RiccioDepartment of Public Medicine, University Federico II, 80131 Naples, Italy.
Camilla RussoDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.ORCID 0000-0002-2256-7281
Giuseppe PontilloDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Roberta EspositoDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Massimo ImbriacoDepartment of Advanced Biomedical Sciences, Federico II University Hospital, 80131 Naples, Italy.
Antonio PisaniDepartment of Public Medicine, University Federico II, 80131 Naples, Italy.
Federico II University Hospital · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we evaluated the possible relationship between the changes in retinal vessel density (VD) by optical coherence tomography angiography (OCTA) and the vascular alterations involving renal, cardiovascular and central nervous systems in patients affected by Fabry disease (FD). In 50 FD patients, the retinal superficial capillary plexus (SCP) and deep capillary plexus (DCP) in macular region were evaluated by OCTA examination. The patients also underwent a brain magnetic resonance imaging scan, renal and echocardiographic examinations with quantification of systolic pulmonary arterial pressure (PAPs) and left atrial volume index (LAVi). The VD of SCP and DCP was inversely related with E/e' ratio, LAVi, interventricular septal thickness, global longitudinal strain (GLS) and PAPs (

Indexed as

echocardiographyFabry diseaseleft atrial volume indexoptical coherence tomography angiographypeak arterial pulmonary pressureretinal vessel densityTSVDS

Identifiers

PMID33352849
PMCPMC7766384
OpenAlexW3111173698

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.