Evidence map›Paper›PMID 33352837›Full record

ArticleJournal of clinical medicine2020

Plasma Endocan as a Predictor of Cardiovascular Event in Patients with End-Stage Renal Disease on Hemodialysis.

Jin Sug Kim, Gang Jee Ko, Yang Gyun Kim, So Young Lee, Dong Young Lee, Kyung Hwan Jeong, Sang Ho Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jin Sug KimDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul 02453, Korea.
Gang Jee KoDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul 02841, Korea.
Yang Gyun KimDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul 02453, Korea.ORCID 0000-0002-3497-5514
So Young LeeDivision of Nephrology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.
Dong Young LeeDivision of Nephrology, Department of Internal Medicine, Veterans Health Service Medical Center, Seoul 05368, Korea.ORCID 0000-0003-4963-8286
Kyung Hwan JeongDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul 02453, Korea.
Sang Ho LeeDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul 02453, Korea.
Kyung Hee University · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocan, a potential biomarker of endothelial dysfunction, is associated with increased cardiovascular risk. We investigated the utility of plasma endocan for predicting cardiovascular risk in end-stage renal disease (ESRD) patients undergoing hemodialysis. Of the 452 patients in the K-cohort, 354 with available plasma endocan levels were enrolled. The correlation between plasma endocan levels and the clinical characteristics of a study population were analyzed. We divided patients into two groups, according to plasma endocan levels, and investigated the predictive value of endocan for the occurrence of cardiovascular events. In a multiple linear regression analysis, plasma endocan levels were positively correlated with previous cardiovascular events and negatively correlated with body mass index, albumin, and triglyceride. Patients with higher plasma endocan levels experienced more frequent cardiovascular events than those with lower plasma endocan levels (12.9% in the lower group vs. 22.7% in the higher group,

Indexed as

biomarkerendocanend-stage renal diseasehemodialysis

Identifiers

PMID33352837
PMCPMC7766985
OpenAlexW3112002739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.