Evidence map›Paper›PMID 33352733›Full record

ArticleCancers2020

Melphalan, Etoposide, and Carboplatin Megatherapy with Autologous Stem Cell Transplantation in Children with Relapsing or Therapy-Resistant Extracranial Germ-Cell Tumors-A Retrospective Analysis.

Marek Ussowicz, Monika Mielcarek-Siedziuk, Jakub Musiał, Mateusz Stachowiak, Jadwiga Węcławek-Tompol, Dorota Sęga-Pondel, Jowita Frączkiewicz, Joanna Trelińska, Anna Raciborska

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Marek UssowiczDepartment of Paediatric Bone Marrow Transplantation, Oncology and Hematology, Wrocław Medical University, 50-367 Wrocław, Poland.ORCID 0000-0001-5725-4835
Monika Mielcarek-SiedziukDepartment of Paediatric Bone Marrow Transplantation, Oncology and Hematology, Wrocław Medical University, 50-367 Wrocław, Poland.
Jakub MusiałDepartment of Pediatric Oncology and Hematology, Clinical Hospital No. 2, 35-301 Rzeszów, Poland.
Mateusz StachowiakDepartment of Paediatric Bone Marrow Transplantation, Oncology and Hematology, Wrocław Medical University, 50-367 Wrocław, Poland.
Jadwiga Węcławek-TompolDepartment of Paediatric Bone Marrow Transplantation, Oncology and Hematology, Wrocław Medical University, 50-367 Wrocław, Poland.
Dorota Sęga-PondelDepartment of Paediatric Bone Marrow Transplantation, Oncology and Hematology, Wrocław Medical University, 50-367 Wrocław, Poland.
Jowita FrączkiewiczDepartment of Paediatric Bone Marrow Transplantation, Oncology and Hematology, Wrocław Medical University, 50-367 Wrocław, Poland.
Joanna TrelińskaDepartment of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, 91-738 Łódź, Poland.
Anna RaciborskaDepartment of Oncology and Surgical Oncology for Children and Youth, Institute of Mother and Child, 01-211 Warsaw, Poland.ORCID 0000-0003-2612-7934
Wroclaw Medical University · PLMedical University of Lodz · PL

Funding

Uniwersytet Medyczny im. Piastów Slaskich we Wroclawiu ST.C200.18.013
6 · The paper itself

Abstract

Pediatric germ cell tumors (GCTs) are a group of chemosensitive malignancies with a 90% curability rate. We report a series of children with relapsing or therapy-resistant GCT treated with melphalan-etoposide-carboplatin high-dose chemotherapy (HDCT) and autologous stem cell transplantation. This consisted of 18 children, either with GCTs after relapse (nine patients) or with an unsatisfactory response to first-line chemotherapy (nine patients), who underwent HDCT. The HDCT regimens MEC1 (carboplatin 1500 mg/m

Indexed as

autologous stem cell transplantationgerm cell tumorshigh dose chemotherapy

Identifiers

PMID33352733
PMCPMC7765864
OpenAlexW3114312350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.