Evidence map›Paper›PMID 33352689›Full record

ArticleInternational journal of molecular sciences2020

Ginsenoside M1 Induces Apoptosis and Inhibits the Migration of Human Oral Cancer Cells.

Yu-Chieh Lee, Wei-Ting Wong, Lan-Hui Li, Lichieh Julie Chu, Mridula P Menon, Chen-Lung Ho, Oleg V Chernikov, Sheau-Long Lee, Kuo-Feng Hua

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Advances in Small Molecular Agents against Oral Cancer.Molecules (Basel, Switzerland) · 2024
    Review
  3. Article
  4. Review
  5. Antifatigue Effect ofFrontiers in nutrition · 2022
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Yu-Chieh LeeDepartment of Biotechnology and Animal Science, National Ilan University, Ilan 260007, Taiwan.
Wei-Ting WongDepartment of Biotechnology and Animal Science, National Ilan University, Ilan 260007, Taiwan.
Lan-Hui LiDepartment of Laboratory Medicine, Linsen, Chinese Medicine and Kunming Branch, Taipei City Hospital, Taipei 10844, Taiwan.
Lichieh Julie ChuMolecular Medicine Research Center, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-8488-9614
Mridula P MenonDepartment of Biotechnology and Animal Science, National Ilan University, Ilan 260007, Taiwan.
Chen-Lung HoDivision of Wood Cellulose, Taiwan Forestry Research Institute, Taipei 100051, Taiwan.
Oleg V ChernikovG.B. Elyakov Pacific Institute of Bioorganic Chemistry FEB RAS, 690022 Vladivostok, Russia.ORCID 0000-0002-3076-3637
Sheau-Long LeeWellhead Biological Technology Corporation, Taoyuan 325, Taiwan.
Kuo-Feng HuaDepartment of Biotechnology and Animal Science, National Ilan University, Ilan 260007, Taiwan.
National Ilan University · TWTri-Service General Hospital · TWChang Gung University · TWPacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RUTaiwan Forestry Research Institute · TW

Funding

Ministry of Science and Technology, Taiwan MOST 108-2628-B-197-001, MOST 109-2628-B-197-001, and MOST 108-2923-B-197-001-MY3
6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) accounts for 5.8% of all malignancies in Taiwan, and the incidence of OSCC is on the rise. OSCC is also a common malignancy worldwide, and the five-year survival rate remains poor. Therefore, new and effective treatments are needed to control OSCC. In the present study, we prepared ginsenoside M1 (20-O-beta-d-glucopyranosyl-20(S)-protopanaxadiol), a major deglycosylated metabolite of ginsenoside, through the biotransformation of

Indexed as

ApoptosisCell MovementAnimalsCell ProliferationGinsenosidesHumansMaleMiceMice, Inbred BALB CMice, NudeMouth NeoplasmsTumor Cells, CulturedXenograft Model Antitumor Assaysginsenoside compound KGinsenosidesapoptosisbiotransformationcaspaseginsenosidemigrationoral squamous cell carcinomaxenograft

Identifiers

PMID33352689
PMCPMC7766606
OpenAlexW3117325185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.