ReviewOpen biology2020
The evolutionary origins of the vertebrate olfactory system.
Review in Open biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 77 citations in OpenAlex.
- Molecular Evidence for the Parallel Evolution of Anosmia in Multiple Odontoceti (Toothed Whales) Clades.Genes · 2026Article
- Single-cell, clonal and spatial atlases of cranial placodes illuminate their specification and evolution.bioRxiv : the preprint server for biology · 2026Article
- The Role of Olfaction in Dogs: Evolution, Biology, and Human-Oriented Work.Animals : an open access journal from MDPI · 2026Review
- Mechanical constraints on cell plasticity: insights from the olfactory epithelium.Frontiers in cell and developmental biology · 2026Review
- Hagfish olfactory repertoire illuminates lineage-specific diversification of olfaction in basal vertebrates.iScience · 2025Article
- Foxg1 and Retinoic Acid Signaling Regulate Zonal Patterning in the Developing Olfactory Epithelium.Development, growth & differentiation · 2025Article
- Lineage-Specific Class-A GPCR Dynamics Reflect Diverse Chemosensory Adaptations in Lophotrochozoa.Molecular biology and evolution · 2025Article
- Airway sensory systems: breathing new life into microbiota-brain communication.Frontiers in cellular neuroscience · 2025Review
- Type 2 vomeronasal receptor expression in the olfactory organ of African lungfish, Protopterus annectens.Cell and tissue research · 2024Article
- Specification of distinct cell types in a sensory-adhesive organ important for metamorphosis in tunicate larvae.PLoS biology · 2024Article
- Diversity and evolution of the vertebrate chemoreceptor gene repertoire.Nature communications · 2024Article
- Evolution of chemosensory tissues and cells across ecologically diverse Drosophilids.Nature communications · 2024Article
- Gene networks and the evolution of olfactory organs, eyes, hair cells and motoneurons: a view encompassing lancelets, tunicates and vertebrates.Frontiers in cell and developmental biology · 2024Review
- Pheromone Perception in Fish: Mechanisms and Modulation by Internal Status.Integrative and comparative biology · 2023Review
- Expanded olfactory system in ray-finned fishes capable of terrestrial exploration.BMC biology · 2023Article
- The Olfactory Bulb in Companion Animals-Anatomy, Physiology, and Clinical Importance.Brain sciences · 2023Review
- Type 1 vomeronasal receptor expression in juvenile and adult lungfish olfactory organ.Zoological letters · 2023Article
- Nasal anatomy and sniffing in respiration and olfaction of wild and domestic animals.Frontiers in veterinary science · 2023Review
- Remarkable diversity of vomeronasal type 2 receptor (OlfC) genes of basal ray-finned fish and its evolutionary trajectory in jawed vertebrates.Scientific reports · 2022Article
- An evolutionary perspective on chordate brain organization and function: insights from amphioxus, and the problem of sentience.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vertebrates develop an olfactory system that detects odorants and pheromones through their interaction with specialized cell surface receptors on olfactory sensory neurons. During development, the olfactory system forms from the olfactory placodes, specialized areas of the anterior ectoderm that share cellular and molecular properties with placodes involved in the development of other cranial senses. The early-diverging chordate lineages amphioxus, tunicates, lampreys and hagfishes give insight into how this system evolved. Here, we review olfactory system development and cell types in these lineages alongside chemosensory receptor gene evolution, integrating these data into a description of how the vertebrate olfactory system evolved. Some olfactory system cell types predate the vertebrates, as do some of the mechanisms specifying placodes, and it is likely these two were already connected in the common ancestor of vertebrates and tunicates. In stem vertebrates, this evolved into an organ system integrating additional tissues and morphogenetic processes defining distinct olfactory and adenohypophyseal components, followed by splitting of the ancestral placode to produce the characteristic paired olfactory organs of most modern vertebrates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.