Evidence map›Paper›PMID 33351800›Full record

ArticlePLoS computational biology2020

IOCBIO Kinetics: An open-source software solution for analysis of data traces.

Marko Vendelin, Martin Laasmaa, Mari Kalda, Jelena Branovets, Niina Karro, Karina Barsunova, Rikke Birkedal

Abstract read
In one paragraph

Article in PLoS computational biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marko VendelinLaboratory of Systems Biology, Department of Cybernetics, School of Science, Tallinn University of Technology, Tallinn, Estonia.ORCID 0000-0002-6459-0391
Martin LaasmaaLaboratory of Systems Biology, Department of Cybernetics, School of Science, Tallinn University of Technology, Tallinn, Estonia.ORCID 0000-0002-6663-6947
Mari KaldaLaboratory of Systems Biology, Department of Cybernetics, School of Science, Tallinn University of Technology, Tallinn, Estonia.ORCID 0000-0002-4705-7237
Jelena BranovetsLaboratory of Systems Biology, Department of Cybernetics, School of Science, Tallinn University of Technology, Tallinn, Estonia.
Niina KarroLaboratory of Systems Biology, Department of Cybernetics, School of Science, Tallinn University of Technology, Tallinn, Estonia.ORCID 0000-0002-3231-0789
Karina BarsunovaLaboratory of Systems Biology, Department of Cybernetics, School of Science, Tallinn University of Technology, Tallinn, Estonia.
Rikke BirkedalLaboratory of Systems Biology, Department of Cybernetics, School of Science, Tallinn University of Technology, Tallinn, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological measurements frequently involve measuring parameters as a function of time, space, or frequency. Later, during the analysis phase of the study, the researcher splits the recorded data trace into smaller sections, analyzes each section separately by finding a mean or fitting against a specified function, and uses the analysis results in the study. Here, we present the software that allows to analyze these data traces in a manner that ensures repeatability of the analysis and simplifies the application of FAIR (findability, accessibility, interoperability, and reusability) principles in such studies. At the same time, it simplifies the routine data analysis pipeline and gives access to a fast overview of the analysis results. For that, the software supports reading the raw data, processing the data as specified in the protocol, and storing all intermediate results in the laboratory database. The software can be extended by study- or hardware-specific modules to provide the required data import and analysis facilities. To simplify the development of the data entry web interfaces, that can be used to enter data describing the experiments, we released a web framework with an example implementation of such a site. The software is covered by open-source license and is available through several online channels.

Indexed as

SoftwareAnimalsBiomedical ResearchDatabases, FactualData Interpretation, StatisticalHumansInternetKineticsUser-Computer Interface

Identifiers

PMID33351800
PMCPMC7787677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.