Evidence map›Paper›PMID 33351755›Full record

ArticleIEEE transactions on medical imaging2021

A Deep Attentive Convolutional Neural Network for Automatic Cortical Plate Segmentation in Fetal MRI.

Haoran Dou, Davood Karimi, Caitlin K Rollins, Cynthia M Ortinau, Lana Vasung, Clemente Velasco-Annis, Abdelhakim Ouaalam, Xin Yang, Dong Ni, Ali Gholipour

Open access · greenAbstract read
In one paragraph

Article in IEEE transactions on medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Article
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  7. Article
  8. Advances in Fetal Brain Imaging.Magnetic resonance imaging clinics of North America · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. BOUNTI: Brain vOlumetry and aUtomated parcellatioN for 3D feTal MRI.bioRxiv : the preprint server for biology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Medical Image Segmentation Using Transformer Networks.IEEE access : practical innovations, open solutions · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Haoran Dou
Davood Karimi
Caitlin K Rollins
Cynthia M Ortinau
Lana Vasung
Clemente Velasco-Annis
Abdelhakim Ouaalam
Xin Yang
Dong Ni
Ali Gholipour
Harvard University · USBoston Children's Hospital · USShenzhen University · CNShenzhen University Health Science Center · CNWashington University in St. Louis · US

Funding

Advancing Microstructural and Vascular Neuroimaging in Perinatal StrokeR01NS106030 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2019 to 2023
$1.7M
Motion-robust super-resolution diffusion weighted MRI of early brain developmentR01EB018988 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI GHOLIPOUR-BABOLI, ALI · 2014 to 2017
$1.6M
Fetal Brain Development in Congenital Heart DiseaseK23NS101120 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI ROLLINS, CAITLIN · 2017 to 2022
$1.1M
Physiologic and Genetic Contributions of Impaired Fetal Brain Development in Congenital Heart DiseaseK23HL141602 · NHLBI · WASHINGTON UNIVERSITY · PI ORTINAU, CYNTHIA MARIE · 2019 to 2022
$727k
NHLBI NIH HHS K23 HL141602NIBIB NIH HHS R01 EB018988NINDS NIH HHS K23 NS101120NINDS NIH HHS R01 NS106030
6 · The paper itself

Abstract

Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and time-consuming. Automatic segmentation of the cortical plate, on the other hand, is challenged by the relatively low resolution of the reconstructed fetal brain MRI scans compared to the thin structure of the cortical plate, partial voluming, and the wide range of variations in the morphology of the cortical plate as the brain matures during gestation. To reduce the burden of manual refinement of segmentations, we have developed a new and powerful deep learning segmentation method. Our method exploits new deep attentive modules with mixed kernel convolutions within a fully convolutional neural network architecture that utilizes deep supervision and residual connections. We evaluated our method quantitatively based on several performance measures and expert evaluations. Results show that our method outperforms several state-of-the-art deep models for segmentation, as well as a state-of-the-art multi-atlas segmentation technique. We achieved average Dice similarity coefficient of 0.87, average Hausdorff distance of 0.96 mm, and average symmetric surface difference of 0.28 mm on reconstructed fetal brain MRI scans of fetuses scanned in the gestational age range of 16 to 39 weeks (28.6± 5.3). With a computation time of less than 1 minute per fetal brain, our method can facilitate and accelerate large-scale studies on normal and altered fetal brain cortical maturation and folding.

Indexed as

Image Processing, Computer-AssistedNeural Networks, ComputerCerebral CortexFetusMagnetic Resonance Imaging

Identifiers

PMID33351755
PMCPMC8016740
OpenAlexW3115552777

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.