Evidence map›Paper›PMID 33351161›Full record

ReviewNano convergence2020

Recent advances in nanomaterial-modified electrical platforms for the detection of dopamine in living cells.

Yeon-Woo Cho, Joon-Ha Park, Kwang-Ho Lee, Taek Lee, Zhengtang Luo, Tae-Hyung Kim

Open access · diamondAbstract readReview
In one paragraph

Review in Nano convergence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Article
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  7. Article
  8. Review
  9. Two-dimensional TiJournal of nanobiotechnology · 2022
    Article
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  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yeon-Woo ChoSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
Joon-Ha ParkSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
Kwang-Ho LeeSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
Taek LeeDepartment of Chemical Engineering, Kwangwoon University, Wolgye-dong, Nowon-gu, 01899, Seoul, Republic of Korea.
Zhengtang LuoDepartment of Chemical and Biological Engineering, Hong Kong University of Science and Technology, Kowloon, 999077, Hong Kong, China.
Tae-Hyung KimSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea. thkim0512@cau.ac.kr.ORCID http://orcid.org/0000-0003-3671-3830
Chung-Ang University · KRHong Kong University of Science and Technology · HKKwangwoon University · KR

Funding

Chung-Ang University (KR) Graduate Research Scholarship in 2020National research foundation of Korea 2019M3A9H2031820National research foundation of Korea 2019R1C1C1007633
6 · The paper itself

Abstract

Dopamine is a key neurotransmitter that plays essential roles in the central nervous system, including motor control, motivation, arousal, and reward. Thus, abnormal levels of dopamine directly cause several neurological diseases, including depressive disorders, addiction, and Parkinson's disease (PD). To develop a new technology to treat such diseases and disorders, especially PD, which is currently incurable, dopamine release from living cells intended for transplantation or drug screening must be precisely monitored and assessed. Owing to the advantages of miniaturisation and rapid detection, numerous electrical techniques have been reported, mostly in combination with various nanomaterials possessing specific nanoscale geometries. This review highlights recent advances in electrical biosensors for dopamine detection, with a particular focus on the use of various nanomaterials (e.g., carbon-based materials, hybrid gold nanostructures, metal oxides, and conductive polymers) on electrode surfaces to improve both sensor performance and biocompatibility. We conclude that this review will accelerate the development of electrical biosensors intended for the precise detection of metabolite release from living cells, which will ultimately lead to advances in therapeutic materials and techniques to cure various neurodegenerative disorders.

Indexed as

Conductive polymersDopamineElectrical detectionGold nanostructureGraphene

Identifiers

PMID33351161
PMCPMC7755953
OpenAlexW3116233583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.