Evidence map›Paper›PMID 33350936›Full record

ArticleeLife2020

Adaptive evolution of an essential telomere protein restricts telomeric retrotransposons.

Bastien Saint-Leandre, Courtney Christopher, Mia T Levine

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. The long reach of the Red Queen.Nature reviews. Genetics · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Sequence, Chromatin and Evolution of Satellite DNA.International journal of molecular sciences · 2021
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Bastien Saint-LeandreDepartment of Biology and Epigenetics Institute, University of Pennsylvania, Philadelphia, United States.
Courtney ChristopherDepartment of Biology and Epigenetics Institute, University of Pennsylvania, Philadelphia, United States.
Mia T LevineDepartment of Biology and Epigenetics Institute, University of Pennsylvania, Philadelphia, United States.ORCID 0000-0003-4311-7535
University of Pennsylvania · US

Funding

Causes and functional consequences of chromatin evolutionR35GM124684 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Mia Tauna Levine · 2017 to 2026
$3.5M
Evolutionary and functional diversification of chromatin proteinsR00GM107351 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI LEVINE, MIA TAUNA · 2015 to 2017
$727k
NIGMS NIH HHS R00 GM107351NIGMS NIH HHS R35 GM124684
6 · The paper itself

Abstract

Essential, conserved cellular processes depend not only on essential, strictly conserved proteins but also on essential proteins that evolve rapidly. To probe this poorly understood paradox, we exploited the rapidly evolving

Indexed as

Biological EvolutionAnimalsChromosomal Proteins, Non-HistoneDrosophilaDrosophila ProteinsRetroelementsTelomerecav protein, DrosophilaChromosomal Proteins, Non-HistoneDrosophila ProteinsRetroelementsconflictD. melanogasterdomesticationessential geneevolutionary biologypositive selectionretrotransposontelomere

Identifiers

PMID33350936
PMCPMC7755394
OpenAlexW3115037091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.