Evidence map›Paper›PMID 33350905›Full record

ArticleEmerging infectious diseases2021

Estimate of Burden and Direct Healthcare Cost of Infectious Waterborne Disease in the United States.

Sarah A Collier, Li Deng, Elizabeth A Adam, Katharine M Benedict, Elizabeth M Beshearse, Anna J Blackstock, Beau B Bruce, Gordana Derado, Chris Edens, Kathleen E Fullerton and 11 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 167 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 5 pooled it
29.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 5 syntheses or guidelines pooled it, 308 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pathogens and global health · 2024
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Microorganisms · 2026
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Are cases of enteric disease due toEnvironmental epidemiology (Philadelphia, Pa.) · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Assessing transcriptomic responses ofMicrobiology spectrum · 2026
    Article
  20. Article

107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Sarah A Collier
Li Deng
Elizabeth A Adam
Katharine M Benedict
Elizabeth M Beshearse
Anna J Blackstock
Beau B Bruce
Gordana Derado
Chris Edens
Kathleen E Fullerton
Julia W Gargano
Aimee L Geissler
Aron J Hall
Arie H Havelaar
Vincent R Hill
Robert M Hoekstra
Sujan C Reddy
Elaine Scallan
Erin K Stokes
Jonathan S Yoder
Michael J Beach
Centers for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Provision of safe drinking water in the United States is a great public health achievement. However, new waterborne disease challenges have emerged (e.g., aging infrastructure, chlorine-tolerant and biofilm-related pathogens, increased recreational water use). Comprehensive estimates of the health burden for all water exposure routes (ingestion, contact, inhalation) and sources (drinking, recreational, environmental) are needed. We estimated total illnesses, emergency department (ED) visits, hospitalizations, deaths, and direct healthcare costs for 17 waterborne infectious diseases. About 7.15 million waterborne illnesses occur annually (95% credible interval [CrI] 3.88 million-12.0 million), results in 601,000 ED visits (95% CrI 364,000-866,000), 118,000 hospitalizations (95% CrI 86,800-150,000), and 6,630 deaths (95% CrI 4,520-8,870) and incurring US $3.33 billion (95% CrI 1.37 billion-8.77 billion) in direct healthcare costs. Otitis externa and norovirus infection were the most common illnesses. Most hospitalizations and deaths were caused by biofilm-associated pathogens (nontuberculous mycobacteria, Pseudomonas, Legionella), costing US $2.39 billion annually.

Indexed as

Communicable DiseasesWaterborne DiseasesHealth Care CostsHospitalizationHumansUnited StatesWater Microbiologybacteriaburden of diseaseCampylobactercost of illnessCryptosporidiumGiardiaLegionellanontuberculous mycobacterianorovirusotitis externaPseudomonasSalmonellaShiga toxin-producing Escherichia coliShigellaUnited StatesVibrioviruseswaterborne

Identifiers

PMID33350905
PMCPMC7774540
OpenAlexW3116770058

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.